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TNFRSF8 recombinant protein :: Tumor necrosis factor receptor superfamily member 8 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS717097
SDS-PAGE
Unit / Price
0.05 mg  /  $770 +1 FREE 8GB USB
0.2 mg  /  $1,030 +1 FREE 8GB USB
0.5 mg  /  $1,140 +1 FREE 8GB USB
1 mg  /  $1,615 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor necrosis factor receptor superfamily member 8 (TNFRSF8), Recombinant Protein

 Also Known As   

Recombinant human Tumor necrosis factor receptor superfamily member 8 protein

 Product Synonym Names    CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30
 Product Gene Name   

TNFRSF8 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    FPQDRPFEDT CHGNPSHYYD KAVRRCCYRC PMGLFPTQQC PQRPTDCRKQ CEPDYYLDEA DRCTACVTCS RDDLVEKTPC AWNSSRVCEC RPGMFCSTSA VNSCARCFFH SVCPAGMIVK FPGTAQKNTV CEPASPGVSP ACASPENCKE PSSGTIPQAK PTPVSPATSS ASTMPVRGGT RLAQEAASKL TRAPDSPSSV GRPSSDPGLS PTQPCPEGSG DCRKQCEPDY YLDEAGRCTA CVSCSRDDLV EKTPCAWNSS RTCECRPGMI CATSATNSCA RCVPYPICAA ETVTKPQDMA EKDTTFEAPP LGTQPDCNPT PENGEAPAST SPTQSLLVDS QASKTLPIPT SAPVALSSTG K
 Chromosome Location    Chromosome: 1; NC_000001.10 (12123434..12204264). Location: 1p36
 OMIM    153243
 3D Structure    ModBase 3D Structure for P28908
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 Host    E Coli
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 Purity/Purification    90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C. For extended storage,conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TNFRSF8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TNFRSF8 recombinant protein

   Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
 Applications Tested/Suitable for TNFRSF8 recombinant protein   

ELISA (EIA), Western Blot (WB)

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 SDS-PAGE of TNFRSF8 recombinant protein    TNFRSF8 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for TNFRSF8. It may not necessarily be applicable to this product.
 NCBI GI #    68348710
 NCBI GeneID    943
 NCBI Accession #    NP_001234.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243.3 [Other Products]
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 UniProt Primary Accession #    P28908 [Other Products]
 UniProt Secondary Accession #    Q6P4D9; B1AN79 [Other Products]
 UniProt Related Accession #    P28908 [Other Products]
 Molecular Weight    66 KD [Similar Products]
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 NCBI Official Full Name    Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 8
 NCBI Official Symbol    TNFRSF8 [Similar Products]
 NCBI Official Synonym Symbols   
CD30; Ki-1; D1S166E
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 8
 UniProt Synonym Protein Names   
CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF8 [Similar Products]
 UniProt Synonym Gene Names    CD30; D1S166E [Similar Products]
 UniProt Entry Name    TNR8_HUMAN
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 NCBI Summary for TNFRSF8    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNFRSF8    Function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

Subunit structure: Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. Ref.8 Ref.9 Ref.10 Ref.11

Subcellular location: Isoform Long: Cell membrane; Single-pass type I membrane protein. Isoform Short: Cytoplasm.

Post-translational modification: Phosphorylated on serine and tyrosine residues. Ref.12

Miscellaneous: Most specific Hodgkin disease associated antigen.

Sequence similarities: Contains 6 TNFR-Cys repeats.
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 Research Articles on TNFRSF8    1. Scattered or diffuse CD30 expression in T-MF was not associated with an absence of CXCR3 expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFRSF8 recombinant proteinPathways associated with TNFRSF8 recombinant protein
 Reference Product  PubMed Publications
 TNFSF8 recombinant protein  >2 publications with TNFRSF8 and TNFSF8
 ALK recombinant protein  >1 publications with TNFRSF8 and ALK
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 TNF-alpha/NF-kB Signaling Pathway antibodies  TNF-alpha/NF-kB Signaling Pathway Diagram
Diseases associated with TNFRSF8 recombinant proteinOrgans/Tissues associated with TNFRSF8 recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >7 publications with TNFRSF8 and Necrosis
 Neoplasms Antibodies  >3 publications with TNFRSF8 and Neoplasms
 Leukemia Antibodies  >2 publications with TNFRSF8 and Leukemia
 Inflammation Antibodies  >2 publications with TNFRSF8 and Inflammation
 Lung Diseases Antibodies  >1 publications with TNFRSF8 and Lung Diseases
 Carcinoma Antibodies  >1 publications with TNFRSF8 and Carcinoma
 Drug Toxicity Antibodies  >1 publications with TNFRSF8 and Drug Toxicity
 Hodgkin Disease Antibodies  >1 publications with TNFRSF8 and Hodgkin Disease
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with TNFRSF8 and Blood
 Mixed Antibodies  >1 publications with TNFRSF8 and Mixed
 Lymph Node Antibodies  >1 publications with TNFRSF8 and Lymph Node
 Lung Antibodies  >1 publications with TNFRSF8 and Lung
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