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TNFRSF9 recombinant protein :: Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS969313
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Unit / Price
0.005 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $430 +1 FREE 8GB USB
0.25 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9) (Active)

 Product Synonym Names    4-1BB ligand receptor; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD antigen CD137
 Product Gene Name   

TNFRSF9 recombinant protein

[Similar Products]
 Product Synonym Gene Name    CD137; ILA [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    19-184aa, Partial
 Sequence    ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS
 OMIM    U03397 mRNA
 3D Structure    ModBase 3D Structure for Q07011
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 Host    E Coli
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 Purity/Purification    >=97% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Biological Activity    Fully biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 ug for both 4-1BB Ligand and 4-1BB Receptor.
 Storage Buffer    0.2 um filtered PBS, pH 7.4,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TNFRSF9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TNFRSF9 recombinant protein

   Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
 Product Categories/Family for TNFRSF9 recombinant protein    Biological Active Protein; Cancer; Tumor Necrosis Factor
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 SDS-PAGE of TNFRSF9 recombinant protein    TNFRSF9 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for TNFRSF9. It may not necessarily be applicable to this product.
 NCBI GI #    5730095
 NCBI GeneID    3604
 NCBI Accession #    NP_001552.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001561.5 [Other Products]
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 UniProt Primary Accession #    Q07011 [Other Products]
 UniProt Related Accession #    Q07011; AAB34924 [Other Products]
 Molecular Weight    17.7 kDa
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 9
 NCBI Official Synonym Full Names    TNF receptor superfamily member 9
 NCBI Official Symbol    TNFRSF9 [Similar Products]
 NCBI Official Synonym Symbols   
ILA; 4-1BB; CD137; CDw137
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 9
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 9
 UniProt Synonym Protein Names   
4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD_antigen: CD137
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF9 [Similar Products]
 UniProt Synonym Gene Names    CD137; ILA [Similar Products]
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 NCBI Summary for TNFRSF9    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNFRSF9    TNFRSF9: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: receptor activity; tumor necrosis factor receptor activity

Biological Process: apoptosis; immune response; inflammatory response; multicellular organismal development; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway
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 Research Articles on TNFRSF9    1. Egr2-driven cell surface proteins LAG-3 and 4-1BB can identify dysfunctional tumor antigen-specific CD8(+) TIL.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFRSF9 recombinant proteinPathways associated with TNFRSF9 recombinant protein
 Reference Product  PubMed Publications
 TNFSF9 recombinant protein  >77 publications with TNFRSF9 and TNFSF9
 TNFRSF4 recombinant protein  >42 publications with TNFRSF9 and TNFRSF4
 FAS recombinant protein  >22 publications with TNFRSF9 and FAS
 IL2RA recombinant protein  >15 publications with TNFRSF9 and IL2RA
 TRAF2 recombinant protein  >15 publications with TNFRSF9 and TRAF2
 IL2 recombinant protein  >6 publications with TNFRSF9 and IL2
 IL2RG recombinant protein  >3 publications with TNFRSF9 and IL2RG
 LRR1 recombinant protein  >1 publications with TNFRSF9 and LRR1
 MAP3K5 recombinant protein  >1 publications with TNFRSF9 and MAP3K5
 IL2RB recombinant protein  >1 publications with TNFRSF9 and IL2RB
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram
Diseases associated with TNFRSF9 recombinant proteinOrgans/Tissues associated with TNFRSF9 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >109 publications with TNFRSF9 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >75 publications with TNFRSF9 and Neoplasms, Experimental
 Inflammation Antibodies  >58 publications with TNFRSF9 and Inflammation
 Lung Diseases Antibodies  >31 publications with TNFRSF9 and Lung Diseases
 Vascular Diseases Antibodies  >25 publications with TNFRSF9 and Vascular Diseases
 Cardiovascular Diseases Antibodies  >25 publications with TNFRSF9 and Cardiovascular Diseases
 Liver Diseases Antibodies  >20 publications with TNFRSF9 and Liver Diseases
 Lung Neoplasms Antibodies  >18 publications with TNFRSF9 and Lung Neoplasms
 Liver Neoplasms Antibodies  >15 publications with TNFRSF9 and Liver Neoplasms
 Atherosclerosis Antibodies  >14 publications with TNFRSF9 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >7 publications with TNFRSF9 and Adipose Tissue
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