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AGTRAP recombinant protein :: Type-1 angiotensin II receptor-associated protein (AGTRAP) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7007448 AGTRAP recombinant protein
Unit / Price
0.01 mg  /  $780 +1 FREE 8GB USB
0.05 mg  /  $1,280 +1 FREE 8GB USB
0.1 mg  /  $2,205 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Type-1 angiotensin II receptor-associated protein (AGTRAP), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Type-1 angiotensin II receptor-associated protein (AGTRAP)

 Product Gene Name   

AGTRAP recombinant protein

[Similar Products]
 Product Synonym Gene Name    ATRAP [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS7007448 COA    COA PDF
 Sequence Positions    1-159aa; full length protein
 Sequence    MELPAVNLKV ILLGHWLLTT WGCIVFSGSY AWANFTILAL GVWAVAQRDS IDAISMFLGG LLATIFLDIV HISIFYPRVS LTDTGRFGVG MAILSLLLKP LSCCFVYHMY RERGGELLVH TGFLGSSQDR SAYQTIDSAE APADPFAVPE GRSQDARGY
 OMIM    608729
 3D Structure    ModBase 3D Structure for Q6RW13
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 Host    Cell Free Expression
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 Form/Format    Liquid containing glycerol
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol.
 Tag Information    Tag type will be determined during the manufacturing process.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of AGTRAP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for AGTRAP recombinant protein    Transmembrane Protein
 Application Notes for AGTRAP recombinant protein    This is a recombinant transmembrane protein expressed in a cell-free expression system.
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NCBI/Uniprot data below describe general gene information for AGTRAP. It may not necessarily be applicable to this product.
 NCBI GI #    93588491
 NCBI GeneID    57085
 NCBI Accession #    NP_001035284.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001040194.1 [Other Products]
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 UniProt Primary Accession #    Q6RW13 [Other Products]
 UniProt Secondary Accession #    Q5SNV4; Q5SNV5; Q96AC0; Q96PL4; Q9NRW9; A8MVQ5 [Other Products]
 UniProt Related Accession #    Q6RW13 [Other Products]
 Molecular Weight    11,948 Da
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 NCBI Official Full Name    type-1 angiotensin II receptor-associated protein isoform b
 NCBI Official Synonym Full Names    angiotensin II receptor associated protein
 NCBI Official Symbol    AGTRAP [Similar Products]
 NCBI Official Synonym Symbols   
ATRAP
[Similar Products]
 NCBI Protein Information    type-1 angiotensin II receptor-associated protein
 UniProt Protein Name    Type-1 angiotensin II receptor-associated protein
 UniProt Synonym Protein Names   
AT1 receptor-associated protein
 Protein Family    Type-1 angiotensin II receptor-associated protein
 UniProt Gene Name    AGTRAP [Similar Products]
 UniProt Synonym Gene Names    ATRAP [Similar Products]
 UniProt Entry Name    ATRAP_HUMAN
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 NCBI Summary for AGTRAP    This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AGTRAP    AGTRAP: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: cell cortex; cytoplasm; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; Golgi membrane; integral to membrane; intracellular membrane-bound organelle; nucleoplasm; plasma membrane

Molecular Function: angiotensin type II receptor activity; protein binding

Biological Process: regulation of blood pressure; response to hypoxia
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 Research Articles on AGTRAP    1. A role for AT1 receptor-associated proteins in blood pressure regulation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AGTRAP recombinant proteinDiseases associated with AGTRAP recombinant protein
 Reference Product  PubMed Publications
 AGTR1 recombinant protein  >3 publications with AGTRAP and AGTR1
 AGT recombinant protein  >2 publications with AGTRAP and AGT
 PITPNC1 recombinant protein  >1 publications with AGTRAP and PITPNC1
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >43 publications with AGTRAP and Cardiovascular Diseases
 Hypertrophy Antibodies  >16 publications with AGTRAP and Hypertrophy
 Disease Models, Animal Antibodies  >15 publications with AGTRAP and Disease Models, Animal
 Inflammation Antibodies  >14 publications with AGTRAP and Inflammation
 Fibrosis Antibodies  >9 publications with AGTRAP and Fibrosis
 Kidney Diseases Antibodies  >8 publications with AGTRAP and Kidney Diseases
 Nervous System Diseases Antibodies  >6 publications with AGTRAP and Nervous System Diseases
 Necrosis Antibodies  >4 publications with AGTRAP and Necrosis
 Metaplasia Antibodies  >2 publications with AGTRAP and Metaplasia
 Lung Diseases Antibodies  >1 publications with AGTRAP and Lung Diseases
Organs/Tissues associated with AGTRAP recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >42 publications with AGTRAP and Blood
 Kidney Antibodies  >31 publications with AGTRAP and Kidney
 Vascular Antibodies  >29 publications with AGTRAP and Vascular
 Heart Antibodies  >27 publications with AGTRAP and Heart
 Muscle Antibodies  >19 publications with AGTRAP and Muscle
 Brain Antibodies  >10 publications with AGTRAP and Brain
 Liver Antibodies  >5 publications with AGTRAP and Liver
 Eye Antibodies  >4 publications with AGTRAP and Eye
 Connective Tissue Antibodies  >4 publications with AGTRAP and Connective Tissue
 Pancreas Antibodies  >4 publications with AGTRAP and Pancreas
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