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YWHAQ recombinant protein :: Tyr-3/trp-5 Monooxygenase Activation Protein Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS143243 YWHAQ recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $3,515 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tyr-3/trp-5 Monooxygenase Activation Protein (YWHAQ), Recombinant Protein

 Also Known As   

Recombinant Human Tyr-3/trp-5 Monooxygenase Activation Protein, Tau

 Product Synonym Names    YWHAQ Human; Tyr-3/Trp- 5 Monooxygenase Activation Protein Theta Human Recombinant; 14-3-3 theta; 14-3-3 tau; 14-3-3 T-cell; HS1; YWHAQ; 1C5; 14-3-3 Tau; Tyr-3/Trp- 5 Monooxygenase Activation Protein Theta
 Product Gene Name   

YWHAQ recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR VISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK MKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE ILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN
 OMIM    609009
 3D Structure    ModBase 3D Structure for P27348
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 Host    E Coli
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 Purity/Purification    Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    YWHAQ solution containing 20mM Tris 7.5.
Sterile filtered colorless solution.
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 Preparation and Storage    YWHAQ Human Recombinant although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
 Other Notes    Small volumes of YWHAQ recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for YWHAQ recombinant protein

   Description: YWHAQ Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 245 amino acids (1-245) and having a molecular mass of 27 kDa. YWHAQ is purified by proprietary chromatographic techniques.

Introduction: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, ?, ?, ?, ?, ?, ? and ? that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.
 Product Categories/Family for YWHAQ recombinant protein    PROTEIN KINASES; Enzymes; 14-3-3
NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.
 NCBI GI #    5803227
 NCBI GeneID    10971
 NCBI Accession #    NP_006817.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006826.3 [Other Products]
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 UniProt Primary Accession #    P27348 [Other Products]
 UniProt Secondary Accession #    Q567U5; Q5TZU8; Q9UP48; D6W4Z5 [Other Products]
 UniProt Related Accession #    P27348 [Other Products]
 Molecular Weight    27,764 Da
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 NCBI Official Full Name    14-3-3 protein theta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
 NCBI Official Symbol    YWHAQ [Similar Products]
 NCBI Official Synonym Symbols   
1C5; HS1; 14-3-3
[Similar Products]
 NCBI Protein Information    14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
 UniProt Protein Name    14-3-3 protein theta
 UniProt Synonym Protein Names   
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAQ [Similar Products]
 UniProt Entry Name    1433T_HUMAN
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 NCBI Summary for YWHAQ    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for YWHAQ    14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: cytoplasmic vesicle membrane; focal adhesion; membrane; cytoplasm; cytosol

Molecular Function: protein domain specific binding; protein binding; protein N-terminus binding

Biological Process: substantia nigra development; apoptosis; small GTPase mediated signal transduction; negative regulation of transcription, DNA-dependent; protein targeting
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 Research Articles on YWHAQ    1. CCL20 and 14-3-3 zeta are molecules that play a putative role during tumorgenesis in pancreas, and may therefore be new parameters for histological diagnosis and discrimination between pancreatic neoplasms and chronic pancreatitis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with YWHAQ recombinant proteinPathways associated with YWHAQ recombinant protein
 Reference Product  PubMed Publications
 YWHAB recombinant protein  >1 publications with YWHAQ and YWHAB
 YWHAH recombinant protein  >1 publications with YWHAQ and YWHAH
 BAD recombinant protein  >1 publications with YWHAQ and BAD
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
Diseases associated with YWHAQ recombinant proteinOrgans/Tissues associated with YWHAQ recombinant protein
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >1 publications with YWHAQ and Adenocarcinoma
 Breast Neoplasms Antibodies  >1 publications with YWHAQ and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with YWHAQ and Muscle
 Brain Antibodies  >4 publications with YWHAQ and Brain
 Nerve Antibodies  >3 publications with YWHAQ and Nerve
 Heart Antibodies  >2 publications with YWHAQ and Heart
 Prostate Antibodies  >2 publications with YWHAQ and Prostate
 Blood Antibodies  >2 publications with YWHAQ and Blood
 Embryonic Tissue Antibodies  >2 publications with YWHAQ and Embryonic Tissue
 Liver Antibodies  >1 publications with YWHAQ and Liver
 Kidney Antibodies  >1 publications with YWHAQ and Kidney
 Placenta Antibodies  >1 publications with YWHAQ and Placenta
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