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Yars recombinant protein :: Tyrosine--tRNA ligase, cytoplasmic (Yars) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1413901 Yars recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,320 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,320 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,540 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,540 +1 FREE 8GB USB
1 mg (E-Coli)  /  $2,180 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,180 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,640 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,640 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tyrosine--tRNA ligase, cytoplasmic (Yars), Recombinant Protein

 Also Known As   

Recombinant Rat Tyrosine--tRNA ligase, cytoplasmic (Yars)

 Product Synonym Names    Tyrosine--tRNA ligase, cytoplasmic; EC=6.1.1.1; Tyrosyl-tRNA synthetase; TyrRS
 Product Gene Name   

Yars recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-528
 Sequence    MGDAPSPEEK LHLITRNLQE VLGEEKLKEI LKERELKVYW GTATTGKPHV AYFVPMSKIA DFLKAGCEVT ILFADLHAYL DNMKAPWELL ELRTSYYENV IKAMLESIGV PLEKLKFTKG TDYQLSKEYT LDVYRLSSLV TQHDAKKAGA EVVKQVEHPL LSGLLYPGLQ ALDEEYLKVD AQFGGIDQRK IFTFAEKYLP TLGYSKRVHL MNPMVPGLTG SKMSSSEEES KIDLLDRKED VKKKLKKAFC EPGNVENNGV LSFVKHVLFP LKSEFVILRD EKWGGNKTYT IYQELEKDFA AEVVHPGDLK NSVEVALNKL LDPIREKFNT PALKKLASAA YPDPSKQKPT AKGPAKSSEP EEIIPSRLDI RVGKILSVEK HPDADSLYVE KIDVGEAEPR TVVSGLVQFV PKEELQDRLV VVLCNLKPQK MRGVDSQGML LCASVEGVSR QVEPLDPPAG SAPGERVFVQ GYEKGQPDEE LKPKKKVFEK LQADFKISDD CVAQWKQTNF MTKLGFVSCK SLKGGNIS
 3D Structure    ModBase 3D Structure for Q4KM49
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Yars recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Yars. It may not necessarily be applicable to this product.
 NCBI GI #    411147388
 NCBI GeneID    313047
 NCBI Accession #    NP_001020867.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001025696.1 [Other Products]
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 UniProt Primary Accession #    Q4KM49 [Other Products]
 UniProt Related Accession #    Q4KM49 [Other Products]
 Molecular Weight    59,115 Da
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 NCBI Official Full Name    tyrosine--tRNA ligase, cytoplasmic
 NCBI Official Synonym Full Names    tyrosyl-tRNA synthetase
 NCBI Official Symbol    Yars [Similar Products]
 NCBI Protein Information    tyrosine--tRNA ligase, cytoplasmic; tyrRS; tyrosyl--tRNA ligase; tyrosyl-tRNA synthetase, cytoplasmic
 UniProt Protein Name    Tyrosine--tRNA ligase, cytoplasmic
 UniProt Synonym Protein Names   
Tyrosyl-tRNA synthetase; TyrRS
 Protein Family    Tyrosine--tRNA ligase
 UniProt Gene Name    Yars [Similar Products]
 UniProt Synonym Gene Names    TyrRS [Similar Products]
 UniProt Entry Name    SYYC_RAT
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 UniProt Comments for Yars    YARS: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr). Defects in YARS are the cause of Charcot-Marie-Tooth disease dominant intermediate type C (CMTDIC). CMTDIC is a form of Charcot-Marie-Tooth disease characterized by clinical and pathologic features intermediate between demyelinating and axonal peripheral neuropathies, and motor median nerve conduction velocities ranging from 25 to 45 m/sec. Belongs to the class-I aminoacyl-tRNA synthetase family.

Protein type: Ligase; EC 6.1.1.1

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: tyrosine-tRNA ligase activity; ATP binding; isoleucine-tRNA ligase activity; tRNA binding

Biological Process: isoleucyl-tRNA aminoacylation; tyrosyl-tRNA aminoacylation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Yars recombinant proteinPathways associated with Yars recombinant protein
 Reference Product  PubMed Publications
 Lars recombinant protein  >2 publications with Yars and Lars
 Rars recombinant protein  >1 publications with Yars and Rars
 Kars recombinant protein  >1 publications with Yars and Kars
 Qars recombinant protein  >1 publications with Yars and Qars
 Iars recombinant protein  >1 publications with Yars and Iars
 Eprs recombinant protein  >1 publications with Yars and Eprs
 Mars recombinant protein  >1 publications with Yars and Mars
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Cytosolic TRNA Aminoacylation Pathway antibodies  Cytosolic TRNA Aminoacylation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
Diseases associated with Yars recombinant proteinOrgans/Tissues associated with Yars recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4 publications with Yars and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >3 publications with Yars and Disease Models, Animal
 Charcot-Marie-Tooth Disease, Dominant Intermediate C Antibodies  >3 publications with Yars and Charcot-Marie-Tooth Disease, Dominant Intermediate C
 Nerve Degeneration Antibodies  >2 publications with Yars and Nerve Degeneration
 Brain Diseases Antibodies  >2 publications with Yars and Brain Diseases
 Inflammation Antibodies  >2 publications with Yars and Inflammation
 Pain Antibodies  >1 publications with Yars and Pain
 Liver Neoplasms Antibodies  >1 publications with Yars and Liver Neoplasms
 Heart Diseases Antibodies  >1 publications with Yars and Heart Diseases
 Kidney Diseases Antibodies  >1 publications with Yars and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >2 publications with Yars and Heart
 Ovary Antibodies  >1 publications with Yars and Ovary
 Embryonic Tissue Antibodies  >1 publications with Yars and Embryonic Tissue
 Liver Antibodies  >1 publications with Yars and Liver
 Kidney Antibodies  >1 publications with Yars and Kidney
 Brain Antibodies  >1 publications with Yars and Brain
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