NP_001016944.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
41,519 Da
NCBI Official Full Name
tyrosyl-DNA phosphodiesterase 2
NCBI Official Synonym Full Names
tyrosyl-DNA phosphodiesterase 2
NCBI Protein Information
tyrosyl-DNA phosphodiesterase 2
UniProt Protein Name
Tyrosyl-DNA phosphodiesterase 2
UniProt Synonym Protein Names
5'-tyrosyl-DNA phosphodiesterase; 5'-Tyr-DNA phosphodiesterase; TRAF and TNF receptor-associated protein homolog
UniProt Synonym Gene Names
ttrap; Tyr-DNA phosphodiesterase 2; 5'-Tyr-DNA phosphodiesterase [Similar Products]
UniProt Comments for tdp2
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals ().
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Products associated with tdp2 recombinant protein
Diseases associated with tdp2 recombinant protein
Organs/Tissues associated with tdp2 recombinant protein
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