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Snrnp70 recombinant protein :: U1 small nuclear ribonucleoprotein 70 kDa (Snrnp70) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1339099 Snrnp70 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $865 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $960 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,085 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,335 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,380 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,460 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,815 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,975 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,015 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,220 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,600 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

U1 small nuclear ribonucleoprotein 70 kDa (Snrnp70), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse U1 small nuclear ribonucleoprotein 70 kDa (Snrnp70)

 Product Synonym Names    U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70
 Product Gene Name   

Snrnp70 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Snrnp70; Snrp70 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-448aa; full length protein
 Sequence    TQFLPPNLL ALFAPRDPIP YLPPLEKLPH EKHHNQPYCG IAPYIREFED PRDAPPPTRA ETREERMERK RREKIERRQQ EVETELKMWD PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS GKPRGYAFIE YEHERDMHSA YKHADGKKID GRRVLVDVER GRTVKGWRPR RLGGGLGGTR RGGADVNIRH SGRDDTSRYD ERPGPSPLPH RDRDRDRERE RRERSRERDK ERERRRSRSR DRRRRSRSRD KDERRRSRER SKDKDRDRKR RSSRSRERAR RERERKEELR GGGGGGGGGS GGGGGGDMAE PSEAGDGAPD DGPPGELGPE GPDGPEEKGR DRDRERRRSH RSERERRRDR DRDRDREHKR GERGSERGRD EARGGGGSGQ DNGLEGLGSD GRDMYMEAEG GDGYMAPENG YLMEAAPE
 3D Structure    ModBase 3D Structure for Q62376
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Snrnp70 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Snrnp70. It may not necessarily be applicable to this product.
 NCBI GI #    67846113
 NCBI GeneID    20637
 NCBI Accession #    NP_033250.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_009224.4 [Other Products]
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 UniProt Primary Accession #    Q62376 [Other Products]
 UniProt Secondary Accession #    Q3UIW4 [Other Products]
 UniProt Related Accession #    Q62376 [Other Products]
 Molecular Weight    19,790 Da
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 NCBI Official Full Name    U1 small nuclear ribonucleoprotein 70 kDa
 NCBI Official Synonym Full Names    small nuclear ribonucleoprotein 70 (U1)
 NCBI Official Symbol    Snrnp70 [Similar Products]
 NCBI Official Synonym Symbols   
70kDa; U1-70; R74807; Snrp70; Srnp70; U1-70K; Rnulp70; AI325098; 2700022N21Rik; 3200002N22Rik
[Similar Products]
 NCBI Protein Information    U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; small nuclear ribonucleoprotein 70kDa (U1); U1 small nuclear ribonucleoprotein polypeptide A; U1 small nuclear ribonucleoprotein 70 kDa polypeptide A
 UniProt Protein Name    U1 small nuclear ribonucleoprotein 70 kDa
 Protein Family    U1 small nuclear ribonucleoprotein
 UniProt Gene Name    Snrnp70 [Similar Products]
 UniProt Synonym Gene Names    Snrp70; U1 snRNP 70 kDa; U1-70K; snRNP70 [Similar Products]
 UniProt Entry Name    RU17_MOUSE
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 NCBI Summary for Snrnp70    This gene encodes a subunit of the U1 snRNP (small nuclear ribonucleic particle), one of at least five snRNPs to comprise the spliceosome, which functions in processing of pre-mRNAs. The U1 snRNP has been shown to be important in defining the 5' splice site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
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 UniProt Comments for Snrnp70    snRNP 70: mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Participates in pre-mRNA splicing and exonic splicing complexes. A major ribonucleoprotein antigen recognized by the sera from patients with autoimmune diseases, such as systemic lupus erythematosus. Four alternatively spliced human isoforms have been described. The truncated isoforms (2-4) cannot bind U1-snRNA.

Protein type: RNA-binding; Spliceosome; RNA splicing

Cellular Component: nucleoplasm; spliceosome; snRNP U1; nucleus; ribonucleoprotein complex

Molecular Function: nucleic acid binding; RNA binding; nucleotide binding

Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome; regulation of RNA splicing
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Snrnp70 recombinant proteinDiseases associated with Snrnp70 recombinant protein
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome, U1-snRNP Pathway antibodies  Spliceosome, U1-snRNP Pathway Diagram
 Spliceosome, U1-snRNP Pathway antibodies  Spliceosome, U1-snRNP Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >19 publications with Snrnp70 and Immune System Diseases
 Kidney Diseases Antibodies  >3 publications with Snrnp70 and Kidney Diseases
 Vascular Diseases Antibodies  >2 publications with Snrnp70 and Vascular Diseases
 Brain Diseases Antibodies  >2 publications with Snrnp70 and Brain Diseases
 Lymphoma Antibodies  >1 publications with Snrnp70 and Lymphoma
 Neoplasms, Experimental Antibodies  >1 publications with Snrnp70 and Neoplasms, Experimental
 Hypertension Antibodies  >1 publications with Snrnp70 and Hypertension
 Breast Neoplasms Antibodies  >1 publications with Snrnp70 and Breast Neoplasms
 Necrosis Antibodies  >1 publications with Snrnp70 and Necrosis
Organs/Tissues associated with Snrnp70 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >10 publications with Snrnp70 and Connective Tissue
 Lung Antibodies  >3 publications with Snrnp70 and Lung
 Kidney Antibodies  >2 publications with Snrnp70 and Kidney
 Salivary Gland Antibodies  >1 publications with Snrnp70 and Salivary Gland
 Spleen Antibodies  >1 publications with Snrnp70 and Spleen
 Skin Antibodies  >1 publications with Snrnp70 and Skin
 Bone Marrow Antibodies  >1 publications with Snrnp70 and Bone Marrow
 Bone Antibodies  >1 publications with Snrnp70 and Bone
 Brain Antibodies  >1 publications with Snrnp70 and Brain
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