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UBE2R2 recombinant protein :: Ubiquitin Conjugating Enzyme E2R 2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144008 UBE2R2 recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $5,015 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ubiquitin Conjugating Enzyme E2R 2 (UBE2R2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Ubiquitin Conjugating Enzyme E2R 2

 Product Synonym Names    UBE2R2 Human; Ubiquitin Conjugating Enzyme E2R 2 Human Recombinant; CDC34B; E2-CDC34B; UBC3B; Ubiquitin carrier protein R2; Ubiquitin-conjugating enzyme E2-CDC34B; Ubiquitin-protein ligase R2; Ubiquitin-conjugating enzyme E2 R2; EC 6.3.2.19
 Product Gene Name   

UBE2R2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MGSMAQ QQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSSDLLY DDLYDDDIDD EDEEEEDADC YDDDDSGNEE S
 OMIM    612506
 3D Structure    ModBase 3D Structure for Q712K3
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 Host    E Coli
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 Purity/Purification    Greater than 85.0% as determined by SDS-PAGE.
 Form/Format    UBE2R2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered clear solution.
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 Other Notes    Small volumes of UBE2R2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for UBE2R2 recombinant protein

   Description: UBE2R2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 261 amino acids (1-238 a.a) and having a molecular mass of 29.6kDa (Molecular size on SDS-PAGE will appear higher).UBE2R2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Ubiquitin-conjugating enzyme E2 R2 (UBE2R2) is a member of the ubiquitin-conjugating enzyme family. Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr
 Product Categories/Family for UBE2R2 recombinant protein    ENZYMES; Enzymes; Ubiquitin Conjugating Enzyme
NCBI/Uniprot data below describe general gene information for UBE2R2. It may not necessarily be applicable to this product.
 NCBI GI #    22212943
 NCBI GeneID    54926
 NCBI Accession #    NP_060281.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_017811.3 [Other Products]
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 UniProt Primary Accession #    Q712K3 [Other Products]
 UniProt Secondary Accession #    Q9NX64; D3DRL5 [Other Products]
 UniProt Related Accession #    Q712K3 [Other Products]
 Molecular Weight    27,166 Da
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 NCBI Official Full Name    ubiquitin-conjugating enzyme E2 R2
 NCBI Official Synonym Full Names    ubiquitin-conjugating enzyme E2R 2
 NCBI Official Symbol    UBE2R2 [Similar Products]
 NCBI Official Synonym Symbols   
UBC3B; CDC34B; E2-CDC34B
[Similar Products]
 NCBI Protein Information    ubiquitin-conjugating enzyme E2 R2; ubiquitin carrier protein R2; ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme UBC3B; ubiquitin-protein ligase R2
 UniProt Protein Name    Ubiquitin-conjugating enzyme E2 R2
 UniProt Synonym Protein Names   
Ubiquitin carrier protein R2; Ubiquitin-conjugating enzyme E2-CDC34B; Ubiquitin-protein ligase R2
 Protein Family    Ubiquitin-conjugating enzyme
 UniProt Gene Name    UBE2R2 [Similar Products]
 UniProt Synonym Gene Names    CDC34B; UBC3B [Similar Products]
 UniProt Entry Name    UB2R2_HUMAN
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 NCBI Summary for UBE2R2    Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for UBE2R2    UBC3B: an E2 ubiquitin conjugating enzyme similar to UBC3/CDC34. Phosphorylation of UBC3B by CK2 induces its interaction with beta-TrCP, regulating beta-TrCP substrate recognition and enhancing beta-catenin degradation.

Protein type: Ubiquitin ligase; Ligase; Ubiquitin conjugating system; EC 6.3.2.19

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: cytoplasm

Molecular Function: small conjugating protein ligase activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding; ligase activity

Biological Process: protein monoubiquitination; proteasomal ubiquitin-dependent protein catabolic process
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 Research Articles on UBE2R2    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with UBE2R2 recombinant proteinPathways associated with UBE2R2 recombinant protein
 Reference Product  PubMed Publications
 SKP1 recombinant protein  >1 publications with UBE2R2 and SKP1
 BTRC recombinant protein  >1 publications with UBE2R2 and BTRC
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
Organs/Tissues associated with UBE2R2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Uncharacterized Tissue Antibodies  >1 publications with UBE2R2 and Uncharacterized Tissue
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