NP_112263.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
16,659 Da
NCBI Official Full Name
ubiquitin-conjugating enzyme E2 D2B
NCBI Official Synonym Full Names
ubiquitin-conjugating enzyme E2D 4 (putative)
NCBI Protein Information
ubiquitin-conjugating enzyme E2 D2B
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 D2B
UniProt Synonym Protein Names
E2 ubiquitin-conjugating enzyme D2B; Ubiquitin carrier protein D2B; Ubiquitin-conjugating enzyme E2(17)KB 2B; Ubiquitin-conjugating enzyme E2-17 kDa 2B; Ubiquitin-protein ligase D2B
UniProt Synonym Gene Names
NCBI Summary for Ube2d2b
ubiquitin-conjugating enzyme (E2 class); mediates the targeting of abnormal and short-lived proteins for degradation [RGD, Feb 2006]
UniProt Comments for Ube2d2b
Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection Plays a role in early maturation of the testis.
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Pathways associated with Ube2d2b recombinant protein
Diseases associated with Ube2d2b recombinant protein
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