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Upk3a recombinant protein :: Uroplakin-3a (Upk3a) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1409416 Upk3a recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $585 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $740 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $785 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $865 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $890 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $995 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,120 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,120 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,130 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,220 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,620 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,705 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,720 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,165 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Uroplakin-3a (Upk3a), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Uroplakin-3a (Upk3a)

 Product Synonym Names    Uroplakin-3a; UP3a; Uroplakin III; UPIII
 Product Gene Name   

Upk3a recombinant protein

[Similar Products]
 Product Synonym Gene Name    Upk3a; Upk3 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1409416 COA    COA PDF
 Sequence Positions    19-207. Partial.
 Sequence    VNLQPQLASV TFATNNPTLT TVALEKPLCM FDSSEPLSGS YEVYLYAMVD SAMSRNVSVQ DSAGVPLSTT FRQTQGGRSG PYKAAAFDLT PCGDLPSLDA VGDVTQASEI LNAYLVRVGN NGTCFWDPNF QGLCNPPLTA ATEYRFKYVL VNMSTGLVQD QTLWSDPIWT NRPIPYSAID TWPGRRSGG
 3D Structure    ModBase 3D Structure for Q9JKX8
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Upk3a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Upk3a. It may not necessarily be applicable to this product.
 NCBI GI #    251823972
 NCBI GeneID    22270
 NCBI Accession #    NP_075967.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_023478.2 [Other Products]
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 UniProt Primary Accession #    Q9JKX8 [Other Products]
 UniProt Secondary Accession #    Q27QV3 [Other Products]
 UniProt Related Accession #    Q9JKX8 [Other Products]
 Molecular Weight    30,990 Da
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 NCBI Official Full Name    uroplakin-3a
 NCBI Official Synonym Full Names    uroplakin 3A
 NCBI Official Symbol    Upk3a [Similar Products]
 NCBI Official Synonym Symbols   
UP3a; Upk3; UPIII; 1110017C07Rik
[Similar Products]
 NCBI Protein Information    uroplakin-3a; uroplakin 3; uroplakin III; proplakin IIIa
 UniProt Protein Name    Uroplakin-3a
 UniProt Synonym Protein Names   
Uroplakin III; UPIII
 Protein Family    Uroplakin
 UniProt Gene Name    Upk3a [Similar Products]
 UniProt Synonym Gene Names    Upk3; UP3a; UPIII [Similar Products]
 UniProt Entry Name    UPK3A_MOUSE
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 UniProt Comments for Upk3a    UPK3A: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. Defects in UPK3A are a cause of renal adysplasia (RADYS); also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy. Belongs to the uroplakin-3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; endoplasmic reticulum; apical plasma membrane; integral to membrane

Biological Process: urinary bladder development; epithelial cell differentiation; urea transport; water transport; cell morphogenesis; sodium ion homeostasis; kidney development; potassium ion homeostasis
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 Research Articles on Upk3a    1. A UPK3A peptide can induce a peptide-specific CD4+ T cell autoimmunity that mediates painful bladder dysfunction in mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Upk3a recombinant proteinOrgans/Tissues associated with Upk3a recombinant protein
 Disease Name  Pubmed Publications
 Urinary Bladder Diseases Antibodies  >30 publications with Upk3a and Urinary Bladder Diseases
 Carcinoma Antibodies  >18 publications with Upk3a and Carcinoma
 Urinary Bladder Neoplasms Antibodies  >15 publications with Upk3a and Urinary Bladder Neoplasms
 Carcinoma, Transitional Cell Antibodies  >9 publications with Upk3a and Carcinoma, Transitional Cell
 Cystitis Antibodies  >7 publications with Upk3a and Cystitis
 Neoplasm Metastasis Antibodies  >5 publications with Upk3a and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >4 publications with Upk3a and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >4 publications with Upk3a and Adenocarcinoma
 Kidney Diseases Antibodies  >3 publications with Upk3a and Kidney Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with Upk3a and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Bladder Antibodies  >31 publications with Upk3a and Bladder
 Lung Antibodies  >4 publications with Upk3a and Lung
 Embryonic Tissue Antibodies  >2 publications with Upk3a and Embryonic Tissue
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