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RELB recombinant protein :: V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2012293 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $260 +1 FREE 8GB USB
0.1 mg  /  $400 +1 FREE 8GB USB
0.2 mg  /  $495 +1 FREE 8GB USB
0.5 mg  /  $955 +1 FREE 8GB USB
1 mg  /  $1,415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB), Recombinant Protein

 Also Known As   

Recombinant V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB)

 Product Gene Name   

RELB recombinant protein

[Similar Products]
 Matching Pairs    Antibody: V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (MBS2006540)
Antigen: V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (MBS2012293)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-LVG KD CTDGVCRVRL RPHVSPRHSF NNLGIQCVRK KEIEAAIERK IQLGIDPYNA GSLKNHQEVD MNVVRICFQA SYRDQQGHLH RMDPILSEPV YDKKSTNTSE LRICRINKES GPCTGGEELY LLCDKVQKED ISVVFSTASW EGRADFSQAD VHRQIAIVFK TPPYEDLEIS EPVTVNVFLQ RLTDGVCSEP LPFTYLPRDH DSYGVDKKRK RGLPDVLGEL SSSDPHGIES KRRKKKPVFL DHFLPGHSSG LFLPPS
 Chromosome Location    Chromosome: 7; NC_000073.6 (19606217..19629440, complement). Location: 7 A3; 7 9.93 cM
 3D Structure    ModBase 3D Structure for Q04863
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Mus musculus (Mouse)
 Expression System    Prokaryotic expression
 Residues    Leu176~Ser436 (Accession # Q04863) with two N-terminal Tags, His-tag and T7-tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of RELB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for RELB recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for RELB recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of RELB recombinant protein    RELB recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for RELB. It may not necessarily be applicable to this product.
 NCBI GI #    31982053
 NCBI GeneID    19698
 NCBI Accession #    NP_033072.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_009046.2 [Other Products]
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 UniProt Primary Accession #    Q04863 [Other Products]
 UniProt Secondary Accession #    Q8VE46 [Other Products]
 UniProt Related Accession #    Q04863 [Other Products]
 Molecular Weight    33.3kDa
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 NCBI Official Full Name    transcription factor RelB
 NCBI Official Synonym Full Names    avian reticuloendotheliosis viral (v-rel) oncogene related B
 NCBI Official Symbol    Relb [Similar Products]
 NCBI Official Synonym Symbols   
shep
[Similar Products]
 NCBI Protein Information    transcription factor RelB
 UniProt Protein Name    Transcription factor RelB
 Protein Family    Antitoxin
 UniProt Gene Name    Relb [Similar Products]
 UniProt Entry Name    RELB_MOUSE
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 UniProt Comments for RELB    RELB: a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65.

Protein type: Transcription factor

Cellular Component: nucleoplasm; cytoskeleton; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; DNA binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; I-kappaB kinase/NF-kappaB cascade; T-helper 1 type immune response; transcription, DNA-dependent; cellular response to stress; rhythmic process; T-helper 1 cell differentiation; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; antigen processing and presentation; regulation of transcription, DNA-dependent; response to cytokine stimulus; innate immune response; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; inflammatory response
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 Research Articles on RELB    1. Data indicate that RelB-silenced dendritic cells (DCs) retain good immune defense function of T cells, and miR-155 might be involved in these differentially modulated processes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RELB recombinant proteinDiseases associated with RELB recombinant protein
 Products by Pathway  Pathway Diagram
 Apoptosis Signaling Pathway antibodies  Apoptosis Signaling Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >191 publications with RELB and Necrosis
 Neoplasms Antibodies  >165 publications with RELB and Neoplasms
 Inflammation Antibodies  >132 publications with RELB and Inflammation
 Breast Neoplasms Antibodies  >28 publications with RELB and Breast Neoplasms
 Nervous System Diseases Antibodies  >22 publications with RELB and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >19 publications with RELB and Cardiovascular Diseases
 Lung Diseases Antibodies  >16 publications with RELB and Lung Diseases
 Prostatic Neoplasms Antibodies  >15 publications with RELB and Prostatic Neoplasms
 Liver Diseases Antibodies  >14 publications with RELB and Liver Diseases
 Kidney Diseases Antibodies  >13 publications with RELB and Kidney Diseases
Organs/Tissues associated with RELB recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >84 publications with RELB and Bone
 Bone Marrow Antibodies  >67 publications with RELB and Bone Marrow
 Spleen Antibodies  >51 publications with RELB and Spleen
 Thymus Antibodies  >39 publications with RELB and Thymus
 Lung Antibodies  >33 publications with RELB and Lung
 Liver Antibodies  >31 publications with RELB and Liver
 Kidney Antibodies  >30 publications with RELB and Kidney
 Muscle Antibodies  >27 publications with RELB and Muscle
 Skin Antibodies  >24 publications with RELB and Skin
 Embryonic Tissue Antibodies  >24 publications with RELB and Embryonic Tissue
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