NP_057292.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,463 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 28 homolog isoform 1
NCBI Official Synonym Full Names
vacuolar protein sorting 28 homolog (S. cerevisiae)
NCBI Protein Information
vacuolar protein sorting-associated protein 28 homolog; ESCRT-I complex subunit VPS28; yeast class E protein Vps28p homolog
UniProt Protein Name
Vacuolar protein sorting-associated protein 28 homolog
UniProt Synonym Protein Names
ESCRT-I complex subunit VPS28
UniProt Synonym Gene Names
UniProt Entry Name
VPS28_HUMAN
NCBI Summary for VPS28
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
UniProt Comments for VPS28
VPS28: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Belongs to the VPS28 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: late endosome membrane; cytoplasm; plasma membrane; endosome membrane; cytosol; endosome
Molecular Function: protein binding; protein complex binding
Biological Process: viral reproduction; ubiquitin-dependent protein catabolic process via the multivesicular body pathway; viral protein processing; negative regulation of protein ubiquitination; viral infectious cycle; virus assembly; endosome transport; protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway
Research Articles on VPS28
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Products associated with VPS28 recombinant protein
Pathways associated with VPS28 recombinant protein
Diseases associated with VPS28 recombinant protein
Organs/Tissues associated with VPS28 recombinant protein
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