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SERPINA12 recombinant protein :: Vaspin Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203100
SDS-Page
Unit / Price
0.1 mg  /  $510 +1 FREE 8GB USB
0.5 mg  /  $1,335 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vaspin (SERPINA12), Recombinant Protein

 Also Known As   

Vaspin, 21- 414aa, Human, His tag, E Coli

 Product Synonym Names    Serine (or cysteine) proteinase inhibitor clade A (alpha-1 antiproteinase antitrypsin) member 12; SERPINA12; serpin peptidase inhibitor clade A member 12; OL-64; Visceral adipose tissue-derived serine protease inhibitor; Serpin A12 precursor; OL64 OL 64; ENSG00000165953; Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 12 antibody
 Product Gene Name   

SERPINA12 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MLKPSFSPRN YKALSEVQGW KQRMAAKELA RQNMDLGFKL LKKLAFYNPG RNIFLSPLSI STAFSMLCLG AQDSTLDEIK QGFNFRKMPE KDLHEGFHYI IHELTQKTQD LKLSIGNTLF IDQRLQPQRK FLEDAKNFYS AETILTNFQN LEMAQKQIND FISQKTHGKI NNLIENIDPG TVMLLANYIF FRARWKHEFD PNVTKEEDFF LEKNSSVKVP MMFRSGIYQV GYDDKLSCTI LEIPYQKNIT AIFILPDEGK LKHLEKGLQV DTFSRWKTLL SRRVVDVSVP RLHMTGTFDL KKTLSYIGVS KIFEEHGDLT KIAPHRSLKV GEAVHKAELK MDERGTEGAA GTGAQTLPME TPLVVKIDKP YLLLIYSEKI PSVLFLGKIV NPIGK
 OMIM    AY326420 mRNA
 3D Structure    ModBase 3D Structure for Q8IW75
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 Host    E Coli
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 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    In 20mM Tris 8.0, 0.2mM PMSF, 10% glycerol
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
 Endotoxin Level    < 1.0 EU per 1 microgram of protein (determined by LAL method)
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of SERPINA12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for SERPINA12 recombinant protein

   Vaspin (visceral adipose-specific SERPIN), a newly identified adipokine, which is a member of serine protease inhibitor family. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that induction of human vaspin mRNA expression in adipose tissue is regulated in a fat depot-specific manner and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. Recombinant human Vaspin fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques
 Product Categories/Family for SERPINA12 recombinant protein    Hormones & Cytokines
 Applications Tested/Suitable for SERPINA12 recombinant protein   

SDS-PAGE

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 SDS-Page of SERPINA12 recombinant protein    SERPINA12 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for SERPINA12. It may not necessarily be applicable to this product.
 NCBI GI #    27777657
 NCBI GeneID    145264
 NCBI Accession #    NP_776249 [Other Products]
 NCBI GenBank Nucleotide #    NM_173850.3 [Other Products]
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 UniProt Primary Accession #    Q8IW75 [Other Products]
 UniProt Related Accession #    Q8IW75 [Other Products]
 Molecular Weight    47 kDa (415 aa), confirmed by MALDI-TOF. [Similar Products]
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 NCBI Official Full Name    serpin A12
 NCBI Official Synonym Full Names    serpin family A member 12
 NCBI Official Symbol    SERPINA12 [Similar Products]
 NCBI Official Synonym Symbols   
OL-64
[Similar Products]
 NCBI Protein Information    serpin A12
 UniProt Protein Name    Serpin A12
 UniProt Synonym Protein Names   
OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin
 Protein Family    Serpin
 UniProt Gene Name    SERPINA12 [Similar Products]
 UniProt Synonym Gene Names    Vaspin [Similar Products]
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 UniProt Comments for SERPINA12    Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
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Product References and Citations for SERPINA12 recombinant protein

   Hida K., et al. (2005) PNAS. 102 (30):10610-5.; Kloting N., et al. (2006) Biochem Biophys Res Commun. 339 (1):430-6;
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 Research Articles on SERPINA12    1. Serum vaspin cannot be used as an independent marker for the presence of coronary artery disease in the general population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SERPINA12 recombinant proteinDiseases associated with SERPINA12 recombinant protein
 Reference Product  PubMed Publications
 ITLN1 recombinant protein  >24 publications with SERPINA12 and ITLN1
 APLN recombinant protein  >15 publications with SERPINA12 and APLN
 ADIPOQ recombinant protein  >12 publications with SERPINA12 and ADIPOQ
 RBP4 recombinant protein  >10 publications with SERPINA12 and RBP4
 RETN recombinant protein  >4 publications with SERPINA12 and RETN
 NAMPT recombinant protein  >4 publications with SERPINA12 and NAMPT
 LEP recombinant protein  >1 publications with SERPINA12 and LEP
 RARRES2 recombinant protein  >1 publications with SERPINA12 and RARRES2
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >92 publications with SERPINA12 and Insulin Resistance
 Inflammation Antibodies  >38 publications with SERPINA12 and Inflammation
 Atherosclerosis Antibodies  >21 publications with SERPINA12 and Atherosclerosis
 Liver Diseases Antibodies  >16 publications with SERPINA12 and Liver Diseases
 Necrosis Antibodies  >14 publications with SERPINA12 and Necrosis
 Heart Diseases Antibodies  >12 publications with SERPINA12 and Heart Diseases
 Weight Loss Antibodies  >12 publications with SERPINA12 and Weight Loss
 Fatty Liver Antibodies  >12 publications with SERPINA12 and Fatty Liver
 Non-alcoholic Fatty Liver Disease Antibodies  >9 publications with SERPINA12 and Non-alcoholic Fatty Liver Disease
 Ovarian Diseases Antibodies  >8 publications with SERPINA12 and Ovarian Diseases
Organs/Tissues associated with SERPINA12 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >23 publications with SERPINA12 and Liver
 Skin Antibodies  >8 publications with SERPINA12 and Skin
 Mouth Antibodies  >1 publications with SERPINA12 and Mouth
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