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Vldlr recombinant protein :: Very low-density lipoprotein receptor (Vldlr) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965268 Vldlr recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,585 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,585 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,815 +2 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,815 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,740 +3 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,740 +3 FREE 8GB USB
1 mg (Yeast)  /  $3,180 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $3,180 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Very low-density lipoprotein receptor (Vldlr), Recombinant Protein

 Also Known As   

Recombinant Mouse Very low-density lipoprotein receptor (Vldlr)

 Product Synonym Names    Very low-density lipoprotein receptor; VLDL receptor; VLDL-R
 Product Gene Name   

Vldlr recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    28-797
 Sequence    GKK AKCDSSQFQC TNGRCITLLW KCDGDEDCAD GSDEKNCVKK TCAESDFVCK NGQCVPNRWQ CDGDPDCEDG SDESPEQCHM RTCRINEISC GARSTQCIPV SWRCDGENDC DNGEDEENCG NITCSADEFT CSSGRCVSRN FVCNGQDDCD DGSDELDCAP PTCGAHEFQC STSSCIPLSW VCDDDADCSD QSDESLEQCG RQPVIHTKCP TSEIQCGSGE CIHKKWRCDG DPDCKDGSDE VNCPSRTCRP DQFECEDGSC IHGSRQCNGI RDCVDGSDEV NCKNVNQCLG PGKFKCRSGE CIDMSKVCDQ EQDCRDWSDE PLKECHINEC LVNNGGCSHI CKDLVIGYEC DCAAGFELID RKTCGDIDEC QNPGICSQIC INLKGGYKCE CSRGYQMDLA TGVCKAVGKE PSLIFTNRRD IRKIGLERKE YIQLVEQLRN TVALDADIAA QKLFWADLSQ KAIFSASIDD KVGRHFKMID NVYNPAAIAV DWVYKTIYWT DAASKTISVA TLDGAKRKFL FNSDLREPAS IAVDPLSGFV YWSDWGEPAK IEKAGMNGFD RRPLVTEDIQ WPNGITLDLV KSRLYWLDSK LHMLSSVDLN GQDRRIVLKS LEFLAHPLAL TIFEDRVYWI DGENEAVYGA NKFTGSELAT LVNNLNDAQD IIVYHELVQP SGKNWCEDDM ENGGCEYLCL PAPQINDHSP KYTCSCPNGY NLEENGRECQ STSTPVTYSE TKDINTTDIL RTSGLVPGGI NVTTAVSEVS VPPKGTS
 3D Structure    ModBase 3D Structure for P98156
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Vldlr recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Vldlr. It may not necessarily be applicable to this product.
 NCBI GI #    238637305
 NCBI GeneID    22359
 NCBI Accession #    NP_001154892.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001161420.1 [Other Products]
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 UniProt Primary Accession #    P98156 [Other Products]
 UniProt Secondary Accession #    Q64022 [Other Products]
 UniProt Related Accession #    P98156 [Other Products]
 Molecular Weight    96,373 Da
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 NCBI Official Full Name    very low-density lipoprotein receptor isoform b
 NCBI Official Synonym Full Names    very low density lipoprotein receptor
 NCBI Official Symbol    Vldlr [Similar Products]
 NCBI Official Synonym Symbols   
AA408956; AI451093; AW047288
[Similar Products]
 NCBI Protein Information    very low-density lipoprotein receptor; VLDL-R; VLDL receptor
 UniProt Protein Name    Very low-density lipoprotein receptor
 Protein Family    Very low-density lipoprotein receptor
 UniProt Gene Name    Vldlr [Similar Products]
 UniProt Synonym Gene Names    VLDL receptor; VLDL-R [Similar Products]
 UniProt Entry Name    VLDLR_MOUSE
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 UniProt Comments for Vldlr    VLDLR: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. Defects in VLDLR are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 1 (CMARQ1); also known as dysequilibrium syndrome (DES) or non- progressive cerebellar disorder with mental retardation. CMARQ1 is a congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation and cerebellar hypoplasia. Additional features include short stature, strabismus, pes planus and, rarely, seizures. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: extracellular space; cell surface; membrane; apical part of cell; perinuclear region of cytoplasm; integral to membrane; coated pit; nucleus; receptor complex

Molecular Function: very-low-density lipoprotein receptor activity; very-low-density lipoprotein binding; protein binding; apolipoprotein binding; calcium ion binding; glycoprotein binding; calcium-dependent protein binding

Biological Process: steroid metabolic process; receptor-mediated endocytosis; cholesterol metabolic process; transport; positive regulation of protein kinase activity; endocytosis; lipid metabolic process; negative regulation of transcription from RNA polymerase II promoter; lipid transport
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 Research Articles on Vldlr    1. these results identify a novel role for the VLDLR as a negative regulator of DC-mediated adaptive immune responses in HDM-induced allergic airway inflammation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Vldlr recombinant proteinPathways associated with Vldlr recombinant protein
 Reference Product  PubMed Publications
 DAB1 recombinant protein  >58 publications with Vldlr and DAB1
 APOE recombinant protein  >43 publications with Vldlr and APOE
 RELN recombinant protein  >15 publications with Vldlr and RELN
 LPL recombinant protein  >15 publications with Vldlr and LPL
 SNX17 recombinant protein  >1 publications with Vldlr and SNX17
 LRPAP1 recombinant protein  >1 publications with Vldlr and LRPAP1
 Products by Pathway  Pathway Diagram
 Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway antibodies  Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway Diagram
 Reelin Signaling Pathway antibodies  Reelin Signaling Pathway Diagram
Diseases associated with Vldlr recombinant proteinOrgans/Tissues associated with Vldlr recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >43 publications with Vldlr and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >27 publications with Vldlr and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >19 publications with Vldlr and Disease Models, Animal
 Fatty Liver Antibodies  >12 publications with Vldlr and Fatty Liver
 Inflammation Antibodies  >11 publications with Vldlr and Inflammation
 Obesity Antibodies  >9 publications with Vldlr and Obesity
 Dysequilibrium syndrome Antibodies  >8 publications with Vldlr and Dysequilibrium syndrome
 Liver Diseases Antibodies  >7 publications with Vldlr and Liver Diseases
 Atrophy Antibodies  >6 publications with Vldlr and Atrophy
 Adenocarcinoma Antibodies  >6 publications with Vldlr and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >99 publications with Vldlr and Brain
 Blood Antibodies  >46 publications with Vldlr and Blood
 Vascular Antibodies  >35 publications with Vldlr and Vascular
 Embryonic Tissue Antibodies  >30 publications with Vldlr and Embryonic Tissue
 Muscle Antibodies  >30 publications with Vldlr and Muscle
 Liver Antibodies  >27 publications with Vldlr and Liver
 Adipose Tissue Antibodies  >20 publications with Vldlr and Adipose Tissue
 Heart Antibodies  >20 publications with Vldlr and Heart
 Ovary Antibodies  >18 publications with Vldlr and Ovary
 Eye Antibodies  >13 publications with Vldlr and Eye
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