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VAMP2 recombinant protein :: Vesicle-associated membrane protein 2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1123065
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vesicle-associated membrane protein 2 (VAMP2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Vesicle-associated membrane protein 2

 Product Synonym Names    Synaptobrevin-2
 Product Gene Name   

VAMP2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1123065 COA    COA PDF
 MBS1123065 Testing Data    Testing Data PDF
 Sequence Positions    1-116aa; Full Length
 Sequence    MSATAATAPP AAPAGEGGPP APPPNLTSNR RLQQTQAQVD EVVDIMRVNV DKVLERDQKL SELDDRADAL QAGASQFETS AAKLKRKYWW KNLKMMIILG VICAIILIII IVYFST
 OMIM    185881
 3D Structure    ModBase 3D Structure for P63027
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of VAMP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for VAMP2 recombinant protein

   Involved in the targeting and/or fusion of transport vesicles to their target membrane. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
 Product Categories/Family for VAMP2 recombinant protein    Cancer
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 SDS-PAGE of VAMP2 recombinant protein    VAMP2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for VAMP2. It may not necessarily be applicable to this product.
 NCBI GI #    172072620
 NCBI GeneID    6844
 NCBI Accession #    NP_055047.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014232.2 [Other Products]
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 UniProt Primary Accession #    P63027 [Other Products]
 UniProt Secondary Accession #    P19065; Q9BUC2 [Other Products]
 UniProt Related Accession #    P63027 [Other Products]
 Molecular Weight    39.35kD
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 NCBI Official Full Name    vesicle-associated membrane protein 2
 NCBI Official Synonym Full Names    vesicle associated membrane protein 2
 NCBI Official Symbol    VAMP2 [Similar Products]
 NCBI Official Synonym Symbols   
SYB2; VAMP-2
[Similar Products]
 NCBI Protein Information    vesicle-associated membrane protein 2
 UniProt Protein Name    Vesicle-associated membrane protein 2
 UniProt Synonym Protein Names   
Synaptobrevin-2
 Protein Family    Vesicle-associated membrane protein
 UniProt Gene Name    VAMP2 [Similar Products]
 UniProt Synonym Gene Names    SYB2; VAMP-2 [Similar Products]
 UniProt Entry Name    VAMP2_HUMAN
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 NCBI Summary for VAMP2    The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
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 UniProt Comments for VAMP2    VAMP2: a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cell junction; clathrin-coated vesicle; cytoplasmic vesicle; cytosol; integral to plasma membrane; intracellular membrane-bound organelle; membrane; neuron projection; perinuclear region of cytoplasm; plasma membrane; secretory granule; secretory granule membrane; SNARE complex; synapse; synaptic vesicle; synaptic vesicle membrane; terminal button; trans-Golgi network; vesicle; voltage-gated potassium channel complex; zymogen granule membrane

Molecular Function: calcium-dependent protein binding; calmodulin binding; identical protein binding; myosin binding; phospholipid binding; protein binding; protein C-terminus binding; protein complex binding; protein self-association; SNAP receptor activity; SNARE binding; syntaxin binding; syntaxin-1 binding

Biological Process: calcium ion-dependent exocytosis; cellular protein metabolic process; cellular response to insulin stimulus; energy reserve metabolic process; eosinophil degranulation; exocytosis; glutamate secretion; Golgi to plasma membrane protein transport; natural killer cell degranulation; neurotransmitter secretion; neutrophil degranulation; post-Golgi vesicle-mediated transport; protein complex assembly; protein transport; regulation of exocytosis; regulation of insulin secretion; response to glucose stimulus; synaptic transmission; synaptic vesicle exocytosis; vesicle fusion; vesicle-mediated transport
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 Research Articles on VAMP2    1. A large vesicular pool of VAMP2 maintained by AP180 is crucial to sustain efficient neurotransmission.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with VAMP2 recombinant proteinPathways associated with VAMP2 recombinant protein
 Reference Product  PubMed Publications
 SNAP25 recombinant protein  >99 publications with VAMP2 and SNAP25
 SNAP23 recombinant protein  >46 publications with VAMP2 and SNAP23
 SYT1 recombinant protein  >20 publications with VAMP2 and SYT1
 INS recombinant protein  >7 publications with VAMP2 and INS
 STXBP1 recombinant protein  >7 publications with VAMP2 and STXBP1
 STXBP3 recombinant protein  >5 publications with VAMP2 and STXBP3
 STX1B recombinant protein  >2 publications with VAMP2 and STX1B
 CPLX1 recombinant protein  >2 publications with VAMP2 and CPLX1
 STX4 recombinant protein  >2 publications with VAMP2 and STX4
 CPLX2 recombinant protein  >1 publications with VAMP2 and CPLX2
 Products by Pathway  Pathway Diagram
 Acetylcholine Neurotransmitter Release Cycle Pathway antibodies  Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dopamine Neurotransmitter Release Cycle Pathway antibodies  Dopamine Neurotransmitter Release Cycle Pathway Diagram
 Effects Of Botulinum Toxin Pathway antibodies  Effects Of Botulinum Toxin Pathway Diagram
 GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies  GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
 Glutamate Neurotransmitter Release Cycle Pathway antibodies  Glutamate Neurotransmitter Release Cycle Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Infectious Disease Pathway antibodies  Infectious Disease Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
Diseases associated with VAMP2 recombinant proteinOrgans/Tissues associated with VAMP2 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >23 publications with VAMP2 and Disease Models, Animal
 Inflammation Antibodies  >11 publications with VAMP2 and Inflammation
 Seizures Antibodies  >8 publications with VAMP2 and Seizures
 Cognition Disorders Antibodies  >6 publications with VAMP2 and Cognition Disorders
 Movement Disorders Antibodies  >6 publications with VAMP2 and Movement Disorders
 Kidney Diseases Antibodies  >5 publications with VAMP2 and Kidney Diseases
 Depressive Disorder Antibodies  >5 publications with VAMP2 and Depressive Disorder
 Memory Disorders Antibodies  >4 publications with VAMP2 and Memory Disorders
 Hypertension Antibodies  >4 publications with VAMP2 and Hypertension
 Neurobehavioral Manifestations Antibodies  >4 publications with VAMP2 and Neurobehavioral Manifestations
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >220 publications with VAMP2 and Brain
 Nerve Antibodies  >177 publications with VAMP2 and Nerve
 Muscle Antibodies  >77 publications with VAMP2 and Muscle
 Pancreas Antibodies  >39 publications with VAMP2 and Pancreas
 Blood Antibodies  >38 publications with VAMP2 and Blood
 Kidney Antibodies  >29 publications with VAMP2 and Kidney
 Eye Antibodies  >19 publications with VAMP2 and Eye
 Embryonic Tissue Antibodies  >14 publications with VAMP2 and Embryonic Tissue
 Salivary Gland Antibodies  >12 publications with VAMP2 and Salivary Gland
 Lung Antibodies  >12 publications with VAMP2 and Lung
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