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vMIP2 recombinant protein :: Viral Macrophage inflammatory Protein-2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144127 vMIP2 recombinant protein
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $1,365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Viral Macrophage inflammatory Protein-2 (vMIP2), Recombinant Protein

 Also Known As   

Recombinant Viral Macrophage inflammatory Protein-2

 Product Synonym Names    MIP2 Viral; MIP-2 Viral Recombinant; MIP-2 Viral; Viral MIP-2; MIP2 Viral; Viral MIP2; Viral Macrophage inflammatory Protein-2
 Product Gene Name   

vMIP2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA
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 Host    E Coli
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 Purity/Purification    Greater than 97.0% as determined by RP-HPLC & SDS-PAGE.
 Form/Format    Lyophilized from 1mg/ml solution containing 20mM Phospahte Buffer, pH 7.4 % 0.15M NaCl.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized CXCL2 Viral in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Biological Activity    Determined by the inhibitory effect on monocyte migration response to human MIP1A using a concentration range of 1 ug-10 ug/ml of viral MIP2 which will inhibit 25ng/ml of human MIP1A.
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 Preparation and Storage    Lyophilized MIP-2 Viral protein although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL2 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of vMIP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for vMIP2 recombinant protein

   Description: MIP-2 Viral Recombinant produced in E Coli is a single,non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7.9 kDa. The MIP-2 is purified by proprietary chromatographic techniques.

Introduction: Viral MIP-2 is closely related to MIP-1alpha, show amino acid sequence similarity of about 41%. At the amino acid sequence level, Viral MIP-1 and Viral MIP-2 share 48% similarity. Viral MIP-1 and Viral MIP-2 are more closely linked to one another phylogenetically than to other human chemokines, signifying that they have gene duplication within the virus rather than by two independent gene aquisitions. Viral MIP-2 binds to the CCR3 chemokine receptor through which eotaxin and other beta chemokines activate eosinophils. Viral MIP-2 activates and chemoattract human eosinphils.
 Product Categories/Family for vMIP2 recombinant protein    CHEMOKINES; Chemokines; GRO
NCBI/Uniprot data below describe general gene information for vMIP2. It may not necessarily be applicable to this product.
 NCBI GI #    8928443
 NCBI GeneID    4961514
 NCBI Accession #    Q98157.1 [Other Products]
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 UniProt Secondary Accession #    Q2HRC3; D0UZM1 [Other Products]
 Molecular Weight    10,486 Da
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 NCBI Official Full Name    Viral macrophage inflammatory protein 2
 NCBI Official Symbol    K4 [Similar Products]
 NCBI Protein Information    interleukin 8-like CC chemokine; K4; vCCL-2; vMIP-II
 UniProt Protein Name    Viral macrophage inflammatory protein 2
 UniProt Synonym Protein Names   
Viral macrophage inflammatory protein II; vMIP-II; vMIP-1B
 UniProt Gene Name    ORF K4 [Similar Products]
 UniProt Synonym Gene Names    vMIP-II [Similar Products]
 UniProt Entry Name    VMI2_HHV8P
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 UniProt Comments for vMIP2    Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
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 Research Articles on vMIP2    1. A dimeric vMIP-II mutant binds to heparin much more tightly than wild-type vMIP-II.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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