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Vsx1 recombinant protein :: Visual system homeobox 1 (Vsx1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1381431 Vsx1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $775 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $885 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,020 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,035 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,140 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,195 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,265 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,295 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,350 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,620 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,860 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,920 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,050 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,475 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Visual system homeobox 1 (Vsx1), Recombinant Protein

 Also Known As   

Recombinant Mouse Visual system homeobox 1 (Vsx1)

 Product Synonym Names    Visual system homeobox 1; Homeodomain protein RINX; Retinal inner nuclear layer homeobox protein; Transcription factor VSX1
 Product Gene Name   

Vsx1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Vsx1; Rinx [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-363aa; full length protein
 Sequence    MTGRDGLSDA RSRSRALAPG CPPTGSRLRS FAINDLLGLE ADLPTPAEPG LRSNSGDPAE AIGSGPGPGP GLCGSCPARG ALPLGLGLLC GFGAQPPSAA AAARARCLLL ADLRLLPSAG PEPAVAQGPV HPPPALGSQQ RSESVSTSDG DSPSEEKNDP KMSLILGKRK KRRHRTVFTA HQLEELEKAF GEAHYPDVYA REMLAAKTEL PEDRIQVWFQ NRRAKWRKRE KRWGGSSVMA EYGLYGAMVR HCIPLPDSVL NSADSLQGSC APWLLGMHKK STGMRKPESE DKLAGLWEFD HLKKGANKDE DGPERGPDET TQNPENSLED VAIDLSSSSR QETKKMPPGS STQLPQPPQV GAS
 3D Structure    ModBase 3D Structure for Q91V10
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Vsx1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Vsx1 recombinant protein

   This protein contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI/Uniprot data below describe general gene information for Vsx1. It may not necessarily be applicable to this product.
 NCBI GI #    16905095
 NCBI GeneID    114889
 NCBI Accession #    NP_473409.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_054068.2 [Other Products]
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 UniProt Primary Accession #    Q91V10 [Other Products]
 UniProt Related Accession #    Q91V10 [Other Products]
 Molecular Weight    38,755 Da
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 NCBI Official Full Name    visual system homeobox 1
 NCBI Official Synonym Full Names    visual system homeobox 1 homolog (zebrafish)
 NCBI Official Symbol    Vsx1 [Similar Products]
 NCBI Official Synonym Symbols   
CHX10-like
[Similar Products]
 NCBI Protein Information    visual system homeobox 1; homeodomain protein RINX; transcription factor VSX1; retinal inner nuclear layer homeobox protein
 UniProt Protein Name    Visual system homeobox 1
 UniProt Synonym Protein Names   
Homeodomain protein RINX; Retinal inner nuclear layer homeobox protein; Transcription factor VSX1
 Protein Family    Visual system homeobox
 UniProt Gene Name    Vsx1 [Similar Products]
 UniProt Synonym Gene Names    Rinx [Similar Products]
 UniProt Entry Name    VSX1_MOUSE
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 UniProt Comments for Vsx1    VSX1: Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Defects in VSX1 are a cause of posterior polymorphous corneal dystrophy type 1 (PPCD1). PPCD1 is a slowly progressive hereditary disorder of the corneal endothelium that leads to a variable degree of visual impairment usually in adulthood. Defects in VSX1 are a cause of keratoconus type 1 (KTCN1). Keratoconus type 1 is a frequent corneal dystrophy with an incidence that varies from 50 to 230 per 100'000. The cornea assumes a conical shape as a result of a progressive non- inflammatory thinning of the corneal stroma. Keratoconus is most often an isolated sporadic condition with cases of autosomal dominant and autosomal recessive transmission. Defects in VSX1 are the cause of craniofacial anomalies and anterior segment dysgenesis syndrome (CAASDS). CAASDS is a disorder with extremely variable expressivity. Clinical features include wide interpupillary distance, abnormal corneal endothelium, unusual pinnae, partially to completely empty sella turcica, posterior fossa cyst, anterior encephalocele, and/or hydrocephalus. Belongs to the paired homeobox family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding

Biological Process: visual perception; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; response to stimulus; neuron development; neuron maturation; retinal bipolar neuron differentiation
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 Research Articles on Vsx1    1. These findings reveal a role for Vsx1 in type 3a bipolar cells and suggest that Vsx1 function is required transiently in this cell type during the postnatal period.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Vsx1 recombinant proteinDiseases associated with Vsx1 recombinant protein
 Reference Product  PubMed Publications
 Irx5 recombinant protein  >2 publications with Vsx1 and Irx5
 Cabp5 recombinant protein  >1 publications with Vsx1 and Cabp5
 Pou4f2 recombinant protein  >1 publications with Vsx1 and Pou4f2
 Foxn4 recombinant protein  >1 publications with Vsx1 and Foxn4
 Disease Name  Pubmed Publications
 Keratoconus Antibodies  >34 publications with Vsx1 and Keratoconus
 Keratoconus 1 Antibodies  >22 publications with Vsx1 and Keratoconus 1
 Corneal Dystrophies, Hereditary Antibodies  >14 publications with Vsx1 and Corneal Dystrophies, Hereditary
 Eye Abnormalities Antibodies  >6 publications with Vsx1 and Eye Abnormalities
 Retinal Diseases Antibodies  >5 publications with Vsx1 and Retinal Diseases
 Empty Sella Syndrome Antibodies  >2 publications with Vsx1 and Empty Sella Syndrome
 Auditory Perceptual Disorders Antibodies  >2 publications with Vsx1 and Auditory Perceptual Disorders
 Brain Diseases Antibodies  >2 publications with Vsx1 and Brain Diseases
 Craniofacial Abnormalities Antibodies  >2 publications with Vsx1 and Craniofacial Abnormalities
 Confusion Antibodies  >1 publications with Vsx1 and Confusion
Organs/Tissues associated with Vsx1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >80 publications with Vsx1 and Eye
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