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WFDC1 recombinant protein :: WAP Four Disulfide Core Domain Protein 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2030487 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
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Unit / Price
0.01 mg  /  $145 +1 FREE 8GB USB
0.05 mg  /  $270 +1 FREE 8GB USB
0.1 mg  /  $420 +1 FREE 8GB USB
0.2 mg  /  $515 +1 FREE 8GB USB
0.5 mg  /  $995 +1 FREE 8GB USB
1 mg  /  $1,480 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WAP Four Disulfide Core Domain Protein 1 (WFDC1), Recombinant Protein

 Also Known As   

Recombinant WAP Four Disulfide Core Domain Protein 1 (WFDC1)

 Product Gene Name   

WFDC1 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: WAP Four Disulfide Core Domain Protein 1 (MBS2026822)
Antigen: WAP Four Disulfide Core Domain Protein 1 (MBS2030487)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF- QGTWEAM LPARLAEKSR AEEVAATGSR QPHADRCPPP PRTLPPGACQ ATRCQADSEC PRHRRCCYNG CAYACLEAVP PPPVLDWLVQ PKPRWLGGNG WLLDGPEEVL QAETCSTTED GAEPLLCPSG YECHILQPGD EAQGIPNHGQ CVKQRRQAEG RVLRQRLHKE YPEGDSKNVA EPGKGQQR
 OMIM    605322
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 Host    Host: E Coli
Source: Prokaryotic expression
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 Purity/Purification    >95%
 Form/Format    Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
 Concentration    6.9 (lot specific)
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 Predicted Molecular Mass    24.1kDa
 Accurate Molecular Mass (KD)    29kDa
 Endotoxin    <1.0EU per 1ug (determined by the LAL method)
 Expression System    Prokaryotic expression
 Tag    two N-terminal Tags, His-tag and T7-tag
 Organism Species    Mus musculus (Mouse)
 Fragment    Gln24~Arg208
 Usage    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of WFDC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for WFDC1 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-Page of WFDC1 recombinant protein    WFDC1 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for WFDC1. It may not necessarily be applicable to this product.
 NCBI GI #    18379353
 NCBI GeneID    58189
 NCBI Accession #    NP_067020.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021197.3 [Other Products]
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 UniProt Secondary Accession #    Q8NC27; Q9HAU1; D3DUL7 [Other Products]
 UniProt Related Accession #    Q9HC57 [Other Products]
 Molecular Weight    23,977 Da
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 NCBI Official Full Name    WAP four-disulfide core domain protein 1 isoform 1
 NCBI Official Synonym Full Names    WAP four-disulfide core domain 1
 NCBI Official Symbol    WFDC1 [Similar Products]
 NCBI Official Synonym Symbols   
PS20
[Similar Products]
 NCBI Protein Information    WAP four-disulfide core domain protein 1
 UniProt Protein Name    WAP four-disulfide core domain protein 1
 UniProt Synonym Protein Names   
Prostate stromal protein ps20; ps20 growth inhibitor
 Protein Family    WAP four-disulfide core domain protein
 UniProt Gene Name    WFDC1 [Similar Products]
 UniProt Synonym Gene Names    PS20 [Similar Products]
 UniProt Entry Name    WFDC1_HUMAN
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 NCBI Summary for WFDC1    This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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 UniProt Comments for WFDC1    WFDC1: Has growth inhibitory activity.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: extracellular space

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: response to drug; negative regulation of cell growth; response to estradiol stimulus; negative regulation of epithelial cell proliferation
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 Research Articles on WFDC1    1. HIV-1 virus transfer among primary CD4+ T-lymphocytes was promoted by ectopic ps20 expression or by exogenous addition of recombinant ps20.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with WFDC1 recombinant proteinDiseases associated with WFDC1 recombinant protein
 Reference Product  PubMed Publications
 CBFA2T3 recombinant protein  >1 publications with WFDC1 and CBFA2T3
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >5 publications with WFDC1 and Carcinoma
 Prostatic Diseases Antibodies  >5 publications with WFDC1 and Prostatic Diseases
 Genital Diseases, Male Antibodies  >5 publications with WFDC1 and Genital Diseases, Male
 Inflammation Antibodies  >2 publications with WFDC1 and Inflammation
 Melanoma Antibodies  >2 publications with WFDC1 and Melanoma
 Congenital Abnormalities Antibodies  >1 publications with WFDC1 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >1 publications with WFDC1 and Disease Models, Animal
 Precancerous Conditions Antibodies  >1 publications with WFDC1 and Precancerous Conditions
 Liver Diseases Antibodies  >1 publications with WFDC1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with WFDC1 and Carcinoma, Hepatocellular
Organs/Tissues associated with WFDC1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >13 publications with WFDC1 and Prostate
 Eye Antibodies  >4 publications with WFDC1 and Eye
 Lung Antibodies  >3 publications with WFDC1 and Lung
 Heart Antibodies  >2 publications with WFDC1 and Heart
 Skin Antibodies  >2 publications with WFDC1 and Skin
 Connective Tissue Antibodies  >1 publications with WFDC1 and Connective Tissue
 Liver Antibodies  >1 publications with WFDC1 and Liver
 Stomach Antibodies  >1 publications with WFDC1 and Stomach
 Uterus Antibodies  >1 publications with WFDC1 and Uterus
 Brain Antibodies  >1 publications with WFDC1 and Brain
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