Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Wnt3a  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • COT (Ab-290) Antibody
 • Helicobacter Pylori Caga (HP-CAGA) ELISA Kit
 • Platelet Antibody (APAB) ELISA Kit
 • Macrophage Inflammatory Protein 1beta (MIP1beta) ELISA Kit
 • Q Fever Antibody (QF-AB) ELISA Kit
 • Dehydroepiandrosterone-S7 (DEHA-S7) ELISA Kit
 • Myosin (MYS) ELISA Kit
 • Pancreatic Lipase (PL) ELISA Kit
 • Procollagen C Proteinase Enhancer 1 (PCPE1) ELISA Kit
 • Pepsinogen C (PGC) ELISA Kit
 • Total Bile Acide (TBA) ELISA Kit
 • Neuronal Apoptosis Inhibitory Protein (NAIP) ELISA Kit
 • Chemokine Like Factor Superfamily 6 (CKLFSF6) ELISA Kit
 • Tyrosine Hydroxylase (TH) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Wnt3a recombinant protein

Scan QR to view Datasheet Catalog #    MBS837831 Wnt3a recombinant protein
Unit / Price
0.01 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $315 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Wnt3a, Recombinant Protein

 Also Known As   

Wnt3a protein (Mouse)

 Product Synonym Names    Wnta-3 protein; wingless-type MMTV integration site family protein; Wnta 3 protein; WNT member 3A protein
 Product Gene Name   

Wnt3a recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    AA sequence (19-352): SYPIWWSLAV GPQYSSLSTQ PILCASIPGL VPKQLRFCRN YVEIMPSVAE GVKAGIQECQ HQFRGRRWN CTTVSNSLAI FGPVLDKATR ESAFVHAIAS AGVAFAVTRS CAEGSAAICG C SSRLQGSPGE GWKWGGCS EDIEFGGMVS REFADARENR PDARSAMNRH NNEAGRQAIA SH MHLKCKCHGL SGSCEVKTCW WSQPDFR TIGDFLKDKY DSASEMVVEK HRESRGWVET LRP RYTYFKVPTE RDLVYYEASP NFCEPNPETG SFGTRD RTCNVSSHGI DGCDLLCCGR GHNA RTERRREKCH CVFHWCCYVS CQECTRVYDV HTCK  
 OMIM    606359
Section Bar
 Host    E. Coli
Section Bar
 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid in 20mM Tris-HCl, pH8.0 with 500mM Arg and 50% glycerol.
 Concentration    0.125 mg/ml (lot specific)
Section Bar
 Protein Type    Recombinant
 Biological Significance    Wnt3ais a ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
 Biohazard    Use standard laboratory precautions when handling this material.
Section Bar
 Preparation and Storage    4 degree C shipping only. Upon receipt store at -20 degree C to -80 degree C. Avoid repeat freeze-thaw cycles.
 Other Notes    Small volumes of Wnt3a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for Wnt3a recombinant protein

   Purified recombinant Wnt3a protein (Mouse)
 Product Categories/Family for Wnt3a recombinant protein    Signal Transduction
NCBI/Uniprot data below describe general gene information for Wnt3a. It may not necessarily be applicable to this product.
 NCBI GI #    14530679
 NCBI GeneID    89780
 NCBI Accession #    BAB61052.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q3SY79; Q3SY80; Q969P2 [Other Products]
 UniProt Related Accession #    P56704 [Other Products]
 Molecular Weight    42,905 Da
Table BarTOPTable Bar
 NCBI Official Full Name    WNT3A
 NCBI Official Synonym Full Names    wingless-type MMTV integration site family, member 3A
 NCBI Official Symbol    WNT3A [Similar Products]
 NCBI Protein Information    protein Wnt-3a
 UniProt Protein Name    Protein Wnt-3a
 UniProt Gene Name    WNT3A [Similar Products]
 UniProt Entry Name    WNT3A_HUMAN
Section Bar
 NCBI Summary for Wnt3a    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for Wnt3a    WNT3A: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. Interacts with PORCN. Interacts with APCDD1 and WLS. Component of the Wnt-Fzd-LRP5-LRP6 signaling complex that contains a WNT protein, a FZD protein and LRP5 or LRP6. Interacts directly in the complex with LRP6. Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q42

Cellular Component: extracellular space; proteinaceous extracellular matrix; cell surface; Golgi lumen; early endosome membrane; endoplasmic reticulum lumen; extracellular region; plasma membrane

Molecular Function: protein domain specific binding; protein binding; frizzled binding; transcription coactivator activity; receptor agonist activity; frizzled-2 binding

Biological Process: positive regulation of mesodermal cell fate specification; axon guidance; extracellular matrix organization and biogenesis; positive regulation of protein binding; cell proliferation in forebrain; positive regulation of transcription, DNA-dependent; positive regulation of receptor internalization; positive regulation of caspase activity; Wnt receptor signaling pathway through beta-catenin; positive regulation of collateral sprouting in the absence of injury; palate development; negative regulation of axon extension involved in axon guidance; Wnt receptor signaling pathway in forebrain neuroblast division; negative regulation of neurogenesis; neuron differentiation; mammary gland development; positive regulation of cell proliferation; positive regulation of B cell proliferation; hemopoiesis; heart looping; dorsoventral neural tube patterning; inner ear morphogenesis; in utero embryonic development; hippocampus development; negative regulation of fat cell differentiation; positive regulation of peptidyl-serine phosphorylation; osteoblast differentiation; paraxial mesodermal cell fate commitment; signalosome assembly; spinal cord association neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of protein amino acid phosphorylation
Table BarTOPTable Bar
 Research Articles on Wnt3a    1. miR-195 is key in regulating cell proliferation, cell cycle and apoptosis through targeting Wnt3a.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with Wnt3a recombinant proteinPathways associated with Wnt3a recombinant protein
 Reference Product  PubMed Publications
 CTNNB1 recombinant protein  >776 publications with Wnt3a and CTNNB1
 DKK1 recombinant protein  >136 publications with Wnt3a and DKK1
 LRP6 recombinant protein  >104 publications with Wnt3a and LRP6
 LRP5 recombinant protein  >98 publications with Wnt3a and LRP5
 FZD1 recombinant protein  >20 publications with Wnt3a and FZD1
 SFRP2 recombinant protein  >17 publications with Wnt3a and SFRP2
 DVL2 recombinant protein  >17 publications with Wnt3a and DVL2
 DVL3 recombinant protein  >12 publications with Wnt3a and DVL3
 FZD8 recombinant protein  >8 publications with Wnt3a and FZD8
 DVL1 recombinant protein  >5 publications with Wnt3a and DVL1
 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Of Signal Transduction Pathway antibodies  Diseases Of Signal Transduction Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
Diseases associated with Wnt3a recombinant proteinOrgans/Tissues associated with Wnt3a recombinant protein
 Disease Name  Pubmed Publications
 Death Antibodies  >51 publications with Wnt3a and Death
 Cardiovascular Diseases Antibodies  >44 publications with Wnt3a and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >38 publications with Wnt3a and Breast Neoplasms
 Embryo Loss Antibodies  >34 publications with Wnt3a and Embryo Loss
 Inflammation Antibodies  >31 publications with Wnt3a and Inflammation
 Necrosis Antibodies  >30 publications with Wnt3a and Necrosis
 Fibrosis Antibodies  >27 publications with Wnt3a and Fibrosis
 Liver Diseases Antibodies  >25 publications with Wnt3a and Liver Diseases
 Liver Neoplasms Antibodies  >19 publications with Wnt3a and Liver Neoplasms
 Brain Diseases Antibodies  >19 publications with Wnt3a and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >57 publications with Wnt3a and Connective Tissue
 Lung Antibodies  >40 publications with Wnt3a and Lung
 Placenta Antibodies  >13 publications with Wnt3a and Placenta
 Testis Antibodies  >6 publications with Wnt3a and Testis
 Trachea Antibodies  >2 publications with Wnt3a and Trachea
 Uncharacterized Tissue Antibodies  >1 publications with Wnt3a and Uncharacterized Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions