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WFS1 recombinant protein :: Wolframin (WFS1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1039162 WFS1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $615 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $765 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $825 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $910 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $910 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,025 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,150 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,150 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,160 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,285 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,660 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,750 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,760 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,215 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Wolframin (WFS1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Wolframin (WFS1) , partial

 Product Gene Name   

WFS1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    653-869. Partial.
 Sequence    RSEGMKVYNS TLTWQQYGAL CGPRAWKETN MARTQILCSH LEGHRVTWTG RFKYVRVTDI DNSAESAINM LPFFIGDWMR CLYGEAYPAC SPGNTSTAEE ELCRLKLLAK HPCHIKKFDR YKFEITVGMP FSSGADGSRS REEDDVTKDI VLRASSEFKS VLLSLRQGSL IEFSTILEGR LGSKWPVFEL KAISCLNCMA QLSPTRRHVK IEHDWRS
 OMIM    116400
 3D Structure    ModBase 3D Structure for O76024
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of WFS1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for WFS1. It may not necessarily be applicable to this product.
 NCBI GI #    224994205
 NCBI GeneID    7466
 NCBI Accession #    NP_001139325.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145853.1 [Other Products]
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 UniProt Primary Accession #    O76024 [Other Products]
 UniProt Secondary Accession #    Q8N6I3; Q9UNW6; B2R797; D3DVT1 [Other Products]
 UniProt Related Accession #    O76024 [Other Products]
 Molecular Weight    100,292 Da
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 NCBI Official Full Name    wolframin
 NCBI Official Synonym Full Names    wolframin ER transmembrane glycoprotein
 NCBI Official Symbol    WFS1 [Similar Products]
 NCBI Official Synonym Symbols   
WFS; WFRS; WFSL; CTRCT41
[Similar Products]
 NCBI Protein Information    wolframin
 UniProt Protein Name    Wolframin
 Protein Family    Wolframin
 UniProt Gene Name    WFS1 [Similar Products]
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 NCBI Summary for WFS1    This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for WFS1    Participates in the regulation of cellular Ca2+ homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca2+ store.
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 Research Articles on WFS1    1. a novel mutation c.2614-2625delCATGGCGCCGTG in the WFS1-gene was identified in a family with autosomal-dominant hereditary hearing impairment
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with WFS1 recombinant proteinPathways associated with WFS1 recombinant protein
 Reference Product  PubMed Publications
 TCF7L2 recombinant protein  >31 publications with WFS1 and TCF7L2
 SLC30A8 recombinant protein  >26 publications with WFS1 and SLC30A8
 CDKAL1 recombinant protein  >26 publications with WFS1 and CDKAL1
 IGF2BP2 recombinant protein  >26 publications with WFS1 and IGF2BP2
 HHEX recombinant protein  >23 publications with WFS1 and HHEX
 CISD2 recombinant protein  >4 publications with WFS1 and CISD2
 ATF6 recombinant protein  >3 publications with WFS1 and ATF6
 SYVN1 recombinant protein  >2 publications with WFS1 and SYVN1
 Products by Pathway  Pathway Diagram
 IRE1alpha Activates Chaperones Pathway antibodies  IRE1alpha Activates Chaperones Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Unfolded Protein Response (UPR) Pathway antibodies  Unfolded Protein Response (UPR) Pathway Diagram
 XBP1(S) Activates Chaperone Genes Pathway antibodies  XBP1(S) Activates Chaperone Genes Pathway Diagram
Diseases associated with WFS1 recombinant proteinOrgans/Tissues associated with WFS1 recombinant protein
 Disease Name  Pubmed Publications
 Wolfram Syndrome Antibodies  >178 publications with WFS1 and Wolfram Syndrome
 Nervous System Diseases Antibodies  >138 publications with WFS1 and Nervous System Diseases
 Kidney Diseases Antibodies  >107 publications with WFS1 and Kidney Diseases
 Atrophy Antibodies  >104 publications with WFS1 and Atrophy
 Diabetes Mellitus, Type 2 Antibodies  >52 publications with WFS1 and Diabetes Mellitus, Type 2
 Mental Disorders Antibodies  >23 publications with WFS1 and Mental Disorders
 Mood Disorders Antibodies  >17 publications with WFS1 and Mood Disorders
 Insulin Resistance Antibodies  >13 publications with WFS1 and Insulin Resistance
 Glucose Intolerance Antibodies  >8 publications with WFS1 and Glucose Intolerance
 Disease Models, Animal Antibodies  >7 publications with WFS1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >41 publications with WFS1 and Pancreas
 Brain Antibodies  >37 publications with WFS1 and Brain
 Nerve Antibodies  >22 publications with WFS1 and Nerve
 Eye Antibodies  >8 publications with WFS1 and Eye
 Heart Antibodies  >7 publications with WFS1 and Heart
 Liver Antibodies  >7 publications with WFS1 and Liver
 Bone Antibodies  >6 publications with WFS1 and Bone
 Kidney Antibodies  >5 publications with WFS1 and Kidney
 Thyroid Antibodies  >3 publications with WFS1 and Thyroid
 Muscle Antibodies  >3 publications with WFS1 and Muscle
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