NP_034377.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
X-ray repair cross-complementing protein 6
NCBI Official Synonym Full Names
X-ray repair complementing defective repair in Chinese hamster cells 6
NCBI Protein Information
X-ray repair cross-complementing protein 6; CTC75; CTCBF; Ku p70; 5'-dRP/AP lyase Ku70; DNA repair protein XRCC6; thyroid autoantigen 70 kDa; ku autoantigen protein p70 homolog; 5'-deoxyribose-5-phosphate lyase Ku70; CTC box-binding factor 75 kDa subunit; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit
UniProt Protein Name
X-ray repair cross-complementing protein 6
UniProt Synonym Protein Names
5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP/AP lyase Ku70; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Ku autoantigen protein p70 homolog
UniProt Synonym Gene Names
UniProt Entry Name
XRCC6_MOUSE
UniProt Comments for XRCC6
Ku70: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. Allows DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.
Protein type: Nuclear receptor co-regulator; RNA-binding; DNA-binding; EC 3.6.4.-; EC 4.2.99.-; Helicase; DNA repair, damage
Cellular Component: nucleoplasm; transcription factor complex; protein complex; membrane; cytoplasm; nucleolus; chromosome; nucleus
Molecular Function: protein C-terminus binding; hydrolase activity; lyase activity; nucleotide binding; telomeric DNA binding; helicase activity; ATP-dependent DNA helicase activity; DNA binding; double-stranded DNA binding; damaged DNA binding; double-stranded telomeric DNA binding; 5'-deoxyribose-5-phosphate lyase activity; catalytic activity; ATP binding
Biological Process: positive regulation of neurogenesis; V(D)J recombination; transcription, DNA-dependent; metabolic process; positive regulation of transcription, DNA-dependent; DNA repair; double-strand break repair via nonhomologous end joining; DNA recombination; regulation of transcription, DNA-dependent; double-strand break repair; positive regulation of transcription from RNA polymerase II promoter; response to ionizing radiation; negative regulation of transcription, DNA-dependent; response to DNA damage stimulus; telomere maintenance
Research Articles on XRCC6
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Pathways associated with XRCC6 recombinant protein
Diseases associated with XRCC6 recombinant protein
Organs/Tissues associated with XRCC6 recombinant protein
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