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Zic1 recombinant protein :: Zinc finger protein ZIC 1 (Zic1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS718209 Zic1 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,225 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,225 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,445 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,445 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,990 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,990 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,455 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,455 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Zinc finger protein ZIC 1 (Zic1), Recombinant Protein

 Also Known As   

Recombinant Mouse Zinc finger protein ZIC 1 (Zic1)

 Product Synonym Names    Zinc finger protein ZIC 1; Zinc finger protein of the cerebellum 1
 Product Gene Name   

Zic1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Zic1; Zic [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-447
 Sequence    MLLDAGPQYP AIGVTTFGAS RHHSAGDVAE RDVGLGINPF ADGMGAFKLN PSSHELASAG QTAFTSQAPG YAAAAALGHH HHPGHVGSYS SAAFNSTRDF LFRNRGFGDA AAAASAQHSL FAASAGGFGG PHGHTDAAGH LLFSGLHEQA AGHASPNVVN GQMRLGFSGD MYPRPEQYGQ VTSPRSEHYA APQLHGYGPM NVNMAAHHGA GAFFRYMRQP IKQELICKWI EPEQLANPKK SCNKTFSTMH ELVTHVTVEH VGGPEQSNHI CFWEECPREG KPFKAKYKLV NHIRVHTGEK PFPCPFPGCG KVFARSENLK IHKRTHTGEK PFKCEFEGCD RRFANSSDRK KHMHVHTSDK PYLCKMCDKS YTHPSSLRKH MKVHESSSQG SQPSPAASSG YESSTPPTIV SPTTDNPTTS SMSPSSSAVH HTAGHSALSS NFNEWYV
 3D Structure    ModBase 3D Structure for P46684
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Zic1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Zic1 recombinant protein

   Zic1; Zic
NCBI/Uniprot data below describe general gene information for Zic1. It may not necessarily be applicable to this product.
 NCBI GI #    42476265
 NCBI GeneID    22771
 NCBI Accession #    NP_033599.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_009573.3 [Other Products]
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 UniProt Primary Accession #    P46684 [Other Products]
 UniProt Secondary Accession #    Q6PAK5; Q80Y18 [Other Products]
 UniProt Related Accession #    P46684 [Other Products]
 Molecular Weight    48,331 Da
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 NCBI Official Full Name    zinc finger protein ZIC 1
 NCBI Official Synonym Full Names    zinc finger protein of the cerebellum 1
 NCBI Official Symbol    Zic1 [Similar Products]
 NCBI Official Synonym Symbols   
ZIC; ZNF201
[Similar Products]
 NCBI Protein Information    zinc finger protein ZIC 1; odd-paired homolog; Zic family member 1 (odd-paired homolog, Drosophila)
 UniProt Protein Name    Zinc finger protein ZIC 1
 UniProt Synonym Protein Names   
Zinc finger protein of the cerebellum 1
 Protein Family    Zinc finger protein
 UniProt Gene Name    Zic1 [Similar Products]
 UniProt Synonym Gene Names    Zic [Similar Products]
 UniProt Entry Name    ZIC1_MOUSE
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 UniProt Comments for Zic1    ZIC1: Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally- located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'- TGGGTGGTC-3'. Belongs to the GLI C2H2-type zinc-finger protein family.

Protein type: Transcription factor; DNA-binding; C2H2-type zinc finger protein

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; nucleic acid binding; DNA binding; metal ion binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; nervous system development; central nervous system development; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; multicellular organismal development; pattern specification process; adult walking behavior; regulation of transcription, DNA-dependent; positive regulation of protein import into nucleus; spinal cord development; positive regulation of transcription from RNA polymerase II promoter; brain development; cell differentiation; skeletal development; regulation of smoothened signaling pathway
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 Research Articles on Zic1    1. Association with DNA-bound Pax3 strengthens the ability of both Zic1 and Gli2 to transactivate Myf5 in the epaxial somite.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Zic1 recombinant proteinOrgans/Tissues associated with Zic1 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >27 publications with Zic1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >20 publications with Zic1 and Congenital Abnormalities
 Nervous System Malformations Antibodies  >17 publications with Zic1 and Nervous System Malformations
 Brain Diseases Antibodies  >16 publications with Zic1 and Brain Diseases
 Abnormalities, Multiple Antibodies  >10 publications with Zic1 and Abnormalities, Multiple
 Neural Tube Defects Antibodies  >7 publications with Zic1 and Neural Tube Defects
 Disease Models, Animal Antibodies  >5 publications with Zic1 and Disease Models, Animal
 Inflammation Antibodies  >3 publications with Zic1 and Inflammation
 Neoplasms, Experimental Antibodies  >3 publications with Zic1 and Neoplasms, Experimental
 Immune System Diseases Antibodies  >3 publications with Zic1 and Immune System Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >63 publications with Zic1 and Brain
 Embryonic Tissue Antibodies  >30 publications with Zic1 and Embryonic Tissue
 Bone Antibodies  >21 publications with Zic1 and Bone
 Spinal Cord Antibodies  >7 publications with Zic1 and Spinal Cord
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