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eIF5A recombinant protein

Scan QR to view Datasheet Catalog #    MBS203210
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

eIF5A, Recombinant Protein

★Popular Item★
 Also Known As   

eIF5A, 1-154aa, Human, E Coli

 Product Synonym Names    Eukaryotic translation initiation factor 5A isoform B; EIF-5A; EIF5A1; eIF5AI; Eukaryotic translation initiation factor 5A isoform B eIF 4D; EIF 5A; eIF 5A 1; eIF 5A1; eIF4D; uORF; uORF A; Eukaryotic initiation factor 5A; Rev binding factor; Eukaryotic initiation factor 5A isoform 1; MGC99547; Eukaryotic translation initiation factor 5A; Eukaryotic translation initiation factor 5A 1; MGC104255.
 Product Gene Name   

eIF5A recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQDGYLS LLQDSGEVRE DLRLPEGDLG KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK
 OMIM    M23419 mRNA
 3D Structure    ModBase 3D Structure for P63241
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In 50 mM Tris-HCl Buffer pH 7.5 containing 10 % glycerol
 Concentration    1.0 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of eIF5A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for eIF5A recombinant protein

   Eukaryotic translation initiation factor 5A (eIF5A) is the only protein Known to contain unusual amino acid formed by the action of deoxyhypusine synthase and deoxyhypusine hydroxylase using spermidine as the substrate. This protein was previously reported to be involved in the first step of peptide bond formation in translation; however more recent work implicates it as a universally conserved translation elongation factor. Modulation of eIF5A has been linked to proliferation and cancer. Recombinant human eIF5A protein was expressed in E. coli and purified by using conventional chromatography techniques.
 Product Categories/Family for eIF5A recombinant protein    Cell Cycle
 Applications Tested/Suitable for eIF5A recombinant protein   

SDS-PAGE

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 SDS-Page of eIF5A recombinant protein    eIF5A recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for eIF5A. It may not necessarily be applicable to this product.
 NCBI GI #    4503545
 NCBI GeneID    1984
 NCBI Accession #    NP_001961 [Other Products]
 NCBI GenBank Nucleotide #    NM_001970.4 [Other Products]
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 UniProt Primary Accession #    P63241 [Other Products]
 UniProt Secondary Accession #    P10159; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2; A8K9A0; D3DTP2 [Other Products]
 Molecular Weight    16.8 kDa (154 aa), confirmed by MALDI-TOF.
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 NCBI Official Full Name    eukaryotic translation initiation factor 5A-1 isoform B
 UniProt Protein Name    Eukaryotic translation initiation factor 5A-1
 UniProt Synonym Protein Names   
Eukaryotic initiation factor 5A isoform 1; eIF-5A; Rev-binding factor; eIF-4D
 Protein Family    Translation initiation factor
 UniProt Gene Name    EIF5A [Similar Products]
 UniProt Synonym Gene Names    eIF-5A-1; eIF-5A1; eIF-5A [Similar Products]
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 UniProt Comments for eIF5A    mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
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Product References and Citations for eIF5A recombinant protein

   Saini P, et al. (2009). Nature. 459 (7243):118-21; Gosslau A., et al. (2009). J Cell Physiol. 219 (2):485-93;
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with eIF5A recombinant proteinPathways associated with eIF5A recombinant protein
 Reference Product  PubMed Publications
 DOHH recombinant protein  >25 publications with eIF5A and DOHH
 EIF5A2 recombinant protein  >15 publications with eIF5A and EIF5A2
 DHPS recombinant protein  >7 publications with eIF5A and DHPS
 CAD recombinant protein  >1 publications with eIF5A and CAD
 Products by Pathway  Pathway Diagram
 Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies  Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
 Hypusine Synthesis From EIF5A-lysine Pathway antibodies  Hypusine Synthesis From EIF5A-lysine Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Translation Factors Pathway antibodies  Translation Factors Pathway Diagram
 EIF5A Regulation In Response To Inhibition Of The Nuclear Export System Pathway antibodies  EIF5A Regulation In Response To Inhibition Of The Nuclear Export System Pathway Diagram
Diseases associated with eIF5A recombinant proteinOrgans/Tissues associated with eIF5A recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >25 publications with eIF5A and Carcinoma
 Inflammation Antibodies  >11 publications with eIF5A and Inflammation
 Lung Diseases Antibodies  >7 publications with eIF5A and Lung Diseases
 Lung Neoplasms Antibodies  >7 publications with eIF5A and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >6 publications with eIF5A and Carcinoma, Hepatocellular
 Necrosis Antibodies  >6 publications with eIF5A and Necrosis
 Cardiovascular Diseases Antibodies  >6 publications with eIF5A and Cardiovascular Diseases
 Ovarian Neoplasms Antibodies  >6 publications with eIF5A and Ovarian Neoplasms
 Breast Neoplasms Antibodies  >5 publications with eIF5A and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with eIF5A and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with eIF5A and Blood
 Brain Antibodies  >10 publications with eIF5A and Brain
 Lung Antibodies  >9 publications with eIF5A and Lung
 Pancreas Antibodies  >8 publications with eIF5A and Pancreas
 Kidney Antibodies  >7 publications with eIF5A and Kidney
 Liver Antibodies  >7 publications with eIF5A and Liver
 Bone Antibodies  >6 publications with eIF5A and Bone
 Lymph Antibodies  >5 publications with eIF5A and Lymph
 Prostate Antibodies  >5 publications with eIF5A and Prostate
 Embryonic Tissue Antibodies  >4 publications with eIF5A and Embryonic Tissue
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