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PP recombinant protein :: infectious bursal disease virus Polyprotein Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1265131
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $285 +1 FREE 8GB USB
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

infectious bursal disease virus Polyprotein (PP), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Avian infectious bursal disease virus Polyprotein

 Product Gene Name   

PP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    723-1012aa; Partial
 3D Structure    ModBase 3D Structure for P15480
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PP recombinant protein

   Capsid protein VP2 self assbles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1. The precursor of VP2 plays an important role in capsid assembly. First, pre-VP2 and VP2 oligomers assble to form a procapsid. Then, the pre-VP2 intermediates may be processed into VP2 proteins by proteolytic cleavage mediated by VP4 to obtain the mature virion. The final capsid is composed of pentamers and hexamers but VP2 has a natural tendency to assble into all-pentameric structures. Therefore pre-VP2 may be required to allow formation of the hexameric structures. Protease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation.
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 SDS-PAGE of PP recombinant protein    PP recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for PP. It may not necessarily be applicable to this product.
 NCBI GI #    130563
 NCBI Accession #    P15480.1 [Other Products]
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 UniProt Primary Accession #    P15480 [Other Products]
 Molecular Weight    36.9kD [Similar Products]
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 NCBI Official Full Name    Structural polyprotein
 UniProt Protein Name    Structural polyprotein
 UniProt Synonym Protein Names   
Precursor of VP2; Pre-VP2
 UniProt Gene Name    PP [Similar Products]
 UniProt Synonym Gene Names    Pre-VP2; p1; p2; p3; p4; NS [Similar Products]
 UniProt Entry Name    POLS_IBDVC
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 UniProt Comments for PP    Capsid protein VP2 self assembles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1 ().
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Product References and Citations for PP recombinant protein

   Nucleotide sequence of infectious bursal disease virus genome segment A delineates two major open reading frames.Spies U., Mueller H., Becht H.Nucleic Acids Res. 17:7982-7982(1989) A comparison of the sequences of segment A of four infectious bursal disease virus strains and identification of a variable region in VP2.Bayliss C.D., Spies U., Shaw K., Peters R.W., Papageorgiou A., Mueller H., Boursnell M.E.G.J. Gen. Virol. 71:1303-1312(1990) Role of Ser-652 and Lys-692 in the protease activity of infectious bursal disease virus VP4 and identification of its substrate cleavage sites.Lejal N., Da Costa B., Huet J.-C., Delmas B.J. Gen. Virol. 81:983-992(2000) The capsid of infectious bursal disease virus contains several small peptides arising from the maturation process of pVP2.Da Costa B., Chevalier C., Henry C., Huet J.-C., Petit S., Lepault J., Boot H., Delmas B.J. Virol. 76:2393-2402(2002) Structure of birnavirus-like particles determined by combined electron cryomicroscopy and X-ray crystallography.Pous J., Chevalier C., Ouldali M., Navaza J., Delmas B., Lepault J.J. Gen. Virol. 86:2339-2346(2005) The birnavirus crystal structure reveals structural relationships among icosahedral viruses.Coulibaly F., Chevalier C., Gutsche I., Pous J., Navaza J., Bressanelli S., Delmas B., Rey F.A.Cell 120:761-772(2005)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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