NP_417172.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
23.3 kDa
NCBI Official Full Name
S-ribosylhomocysteine lyase
NCBI Protein Information
S-ribosylhomocysteine lyase
UniProt Protein Name
S-ribosylhomocysteine lyase
UniProt Synonym Protein Names
AI-2 synthesis protein; Autoinducer-2 production protein LuxS
UniProt Synonym Gene Names
UniProt Entry Name
LUXS_ECOLI
NCBI Summary for luxS
Escherichia coli luxS is capable of inducing V. harveyi luminescence. [More information is available at EcoGene: EG12712]. LuxS is involved in biosynthesis of autoinducer, the hormone-like signal that mediates cell-cell communication during quorum sensing, the response to increased cell density . [More information is available at EcoCyc: EG12712].
UniProt Comments for luxS
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
Product References and Citations for luxS recombinant protein
Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.DNA Res. 4:91-113(1997)
The complete genome sequence of Escherichia coli K-12.Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.Science 277:1453-1462(1997)
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.Mol. Syst. Biol. 2:E1-E5(2006)
Sequence of minutes 4-25 of Escherichia coli.Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W. Emr, an Escherichia coli locus for multidrug resistance.Lomovskaya O., Lewis K.Proc. Natl. Acad. Sci. U.S.A. 89:8938-8942(1992)
Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.Link A.J., Robison K., Church G.M.Electrophoresis 18:1259-1313(1997)
Detection of new genes in a bacterial genome using Markov models for three gene classes.Borodovsky M., McIninch J., Koonin E.V., Rudd K.E., Medigue C., Danchin A.Nucleic Acids Res. 23:3554-3562(1995)
Quorum sensing in Escherichia coli and Salmonella typhimurium.Surette M.G., Bassler B.L.Proc. Natl. Acad. Sci. U.S.A. 95:7046-7050(1998)
Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi a new family of genes responsible for autoinducer production.Surette M.G., Miller M.B., Bassler B.L.Proc. Natl. Acad. Sci. U.S.A. 96:1639-1644(1999)
Research Articles on luxS
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Products associated with luxS recombinant protein
Pathways associated with luxS recombinant protein
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