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FIB1 recombinant protein :: rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1300267
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $125 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $220 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $350 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $560 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $840 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $920 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $985 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,130 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,225 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,240 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,280 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,445 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,785 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,855 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,940 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,375 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1), Recombinant Protein

 Also Known As   

Recombinant Arabidopsis thaliana rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1)

 Product Synonym Names    rRNA 2'-O-methyltransferase fibrillarin 1; EC=2.1.1.-; SKP1-interacting partner 7
 Product Gene Name   

FIB1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    FIB1; FBR1; SKIP7; At5g52470; K24M7.22 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1300267 COA    COA PDF
 Sequence Positions    1-308aa; Full Length
 Sequence    MRPPVTGGRG GGGFRGGRDG GGRGFGGGRS FGGGRSGDRG RSGPRGRGRG APRGRGGPPR GGMKGGSKVI VEPHRHAGVF IAKGKEDALV TKNLVPGEAV YNEKRISVQN EDGTKVEYRV WNPFRSKLAA AILGGVDNIW IKPGAKVLYL GAASGTTVSH VSDLVGPEGC VYAVEFSHRS GRDLVNMAKK RTNVIPIIED ARHPAKYRML VGMVDVIFSD VAQPDQARIL ALNASFFLKT GGHFVISIKA NCIDSTVAAE AVFQSEVKKL QQEQFKPAEQ VTLEPFERDH ACVVGGYRMP KKQKTPAS
 3D Structure    ModBase 3D Structure for Q9FEF8
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Arabidopsis thaliana (Mouse-ear cress)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FIB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for FIB1 recombinant protein

   Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus
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 SDS-PAGE of FIB1 recombinant protein    FIB1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for FIB1. It may not necessarily be applicable to this product.
 NCBI GI #    186531481
 NCBI GeneID    835323
 NCBI Accession #    NP_001119418.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001125946.1 [Other Products]
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 UniProt Primary Accession #    Q9FEF8 [Other Products]
 UniProt Secondary Accession #    Q0WLG3; Q9FUZ8; Q9SP30; B3H6E7 [Other Products]
 UniProt Related Accession #    Q9FEF8 [Other Products]
 Molecular Weight    29,213 Da
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 NCBI Official Full Name    probable mediator of RNA polymerase II transcription subunit 36b
 NCBI Official Symbol    FIB1 [Similar Products]
 NCBI Official Synonym Symbols   
ATFBR1; ATFIB1; FBR1; FIB1; fibrillarin 1; FIBRILLARIN 1; K24M7.22; K24M7_22; SKIP7; SKP1/ASK1-INTERACTING PROTEIN
[Similar Products]
 NCBI Protein Information    probable mediator of RNA polymerase II transcription subunit 36b
 UniProt Protein Name    Probable mediator of RNA polymerase II transcription subunit 36b
 UniProt Synonym Protein Names   
Histone-glutamine methyltransferase; SKP1-interacting partner 7; rRNA 2'-O-methyltransferase fibrillarin 1 (EC:2.1.1.-)
 UniProt Gene Name    MED36B [Similar Products]
 UniProt Synonym Gene Names    FBR1; FIB1; MED36_2; SKIP7 [Similar Products]
 UniProt Entry Name    MD36B_ARATH
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 UniProt Comments for FIB1    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors ().
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FIB1 recombinant proteinOrgans/Tissues associated with FIB1 recombinant protein
 Products by Pathway  Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Flower Antibodies  >1 publications with FIB1 and Flower
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