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WIBG recombinant protein :: within BCGN Homolog Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144082 WIBG recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $5,015 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

within BCGN Homolog (WIBG), Recombinant Protein

 Also Known As   

Recombinant Human within BCGN Homolog

 Product Synonym Names    WIBG Human; within BCGN Homolog Human Recombinant; PYM; Partner of Y14 and mago; MGC13064; WIBG; BCGN Homolog; Protein wibg homolog
 Product Gene Name   

WIBG recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MEAAGSPAAT ETGKYIASTQ RPDGTWRKQR RVKEGYVPQE EVPVYENKYV KFFKSKPELP PGLSPEATAP VTPSRPEGGE PGLSKTAKRN LKRKEKRRQQ QEKGEAEALS RTLDKVSLEE TAQLPSAPQG SRAAPTAASD QPDSAATTEK AKKIKNLKKK LRQVEELQQR IQAGEVSQPS KEQLEKLARR RALEEELEDL ELGLLEHHHH HH.
 3D Structure    ModBase 3D Structure for Q9BRP8
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 Host    E Coli
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 Purity/Purification    Greater than 85.0% as determined by SDS-PAGE.
 Form/Format    WIBG Human solution containing 20mM Tris pH-8, 0.1M NaCl & 10% glycerol.
Sterile filtered colorless solution.
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 Preparation and Storage    WIBG Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
 Other Notes    Small volumes of WIBG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for WIBG recombinant protein

   Description: WIBG Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-204 a.a.) and having a molecular mass of 23.7 kDa. The WIBG is fused to 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

Introduction: WIBG is a cooperateing partner of Mago-Y14. The Mago-Y14 heterodimer is a key protein of the EJC(exon junction complex) that is deposited on mRNAs as a consequence of splicing and influences postsplicing mRNA metabolism. WIBG is a cytoplasmic RNA-binding protein that is excluded from the nucleus by Crm1. WIBG relates directly with Mago-Y14 by means of its N-terminal domain.
 Product Categories/Family for WIBG recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
NCBI/Uniprot data below describe general gene information for WIBG. It may not necessarily be applicable to this product.
 NCBI GI #    219803946
 NCBI GeneID    84305
 NCBI Accession #    NP_001137325.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001143853.1 [Other Products]
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 UniProt Primary Accession #    Q9BRP8 [Other Products]
 UniProt Secondary Accession #    Q8IXJ8; Q8N8E7; B6ZDM5 [Other Products]
 UniProt Related Accession #    Q9BRP8 [Other Products]
 Molecular Weight    22,705 Da
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 NCBI Official Full Name    partner of Y14 and mago isoform 2
 NCBI Official Synonym Full Names    within bgcn homolog (Drosophila)
 NCBI Official Symbol    WIBG [Similar Products]
 NCBI Official Synonym Symbols   
PYM
[Similar Products]
 NCBI Protein Information    partner of Y14 and mago; protein wibg homolog
 UniProt Protein Name    Partner of Y14 and mago
 UniProt Synonym Protein Names   
Protein wibg homolog
 UniProt Gene Name    WIBG [Similar Products]
 UniProt Synonym Gene Names    PYM [Similar Products]
 UniProt Entry Name    WIBG_HUMAN
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 UniProt Comments for WIBG    WIBG: a conserved protein of unknown function. A potential RNA-binding protein.

Protein type: RNA-binding; Nucleolus; Translation

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus

Molecular Function: protein binding; ribosome binding

Biological Process: positive regulation of translation; mRNA catabolic process, nonsense-mediated decay
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 Research Articles on WIBG    1. PYM is an Exon junction complexes(EJC) disassembly factor that acts both in vitro and in living cells, and that antagonizes important EJC functions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with WIBG recombinant proteinPathways associated with WIBG recombinant protein
 Reference Product  PubMed Publications
 MAGOH recombinant protein  >1 publications with WIBG and MAGOH
 Products by Pathway  Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
Organs/Tissues associated with WIBG recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with WIBG and Bone
 Liver Antibodies  >1 publications with WIBG and Liver
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