View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List IgG secondary antibody :: IgG Fc fragment Secondary Antibody Catalog # MBS719658 Unit / Price 0.5 mg / $200 +1 FREE 8GB USB 5x0.5 mg / $900 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IgG Fc fragment, Secondary Antibody Popular Item Full Product Name Rabbit anti-Human IgG Fc fragment polyclonal Antibody, HRP conjugated Product Synonym Names fragment crystallizable region Product Gene Name IgG secondary antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP MBS719658 COA COA PDF MBS719658 MSDS MSDS PDF MBS719658 Technical Datasheet Technical Datasheet PDF Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human Purity/Purification Caprylic Acid Ammonium Sulfate Precipitation purified Form/Format Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Immunogen Human IgG Fc fragment Conjugate HRP conjugated Product Type Secondary Antibody Preparation and Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of IgG secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for IgG secondary antibody Relevance: The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2-4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6 linked sialic acid residues. Applications Tested/Suitable for IgG secondary antibody ELISA (EIA), Western Blot (WB) Application Notes for IgG secondary antibody WB: 1:500-1:5000 Western Blot (WB) of IgG secondary antibody Western BlotPositive WB detected in Recombinantprotein (80ng, 40ng, 20ng, 10ng)All lanes: Human IgG Fc antibody;HRPconjugated at 1:1000Predicted band size: 35 kDaObserved band size: 35 kDa TOP NCBI Summary for IgG This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008] TOP UniProt Comments for IgG FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells.Protein type: Cell surface; Membrane protein, integral; Receptor, misc.Chromosomal Location of Human Ortholog: 1q23Cellular Component: plasma membrane; integral to membraneMolecular Function: IgG bindingBiological Process: innate immune responseDisease: Systemic Lupus Erythematosus; Malaria, Susceptibility To Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP