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NT small molecule :: Neurotensin (NT) Small Molecule

Scan QR to view Datasheet Catalog #    MBS2086444 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.05 mg  /  $145 +1 FREE 8GB USB
0.01 mg  /  $200 +1 FREE 8GB USB
0.1 mg  /  $200 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neurotensin (NT), Small Molecule

 Also Known As   

OVA Conjugated Neurotensin (NT)

 Product Synonym Names    NTS; NTS1; NmN-125; NN; Tail peptide; Large neuromedin N
 Product Gene Name   

NT small molecule

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    U91618 mRNA
 3D Structure    ModBase 3D Structure for P30990
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 Host    Protein Conjugation
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 Purity/Purification    > 90%
 Form/Format    Freeze-dried powder
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 Buffer Formulation    PBS, pH7.4.
 Organism Species    Rat
 Usage    Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of NT small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for NT small molecule    Conjugated small molecules
 Applications Tested/Suitable for NT small molecule   

Immunogen, SDS-PAGE, Western Blot (WB)

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  of NT small molecule    NT small molecule  image
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NCBI/Uniprot data below describe general gene information for NT. It may not necessarily be applicable to this product.
 NCBI GI #    5453816
 NCBI GeneID    4922
 NCBI Accession #    NP_006174.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006183.4 [Other Products]
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 UniProt Primary Accession #    P30990 [Other Products]
 UniProt Related Accession #    P30990 [Other Products]
 Molecular Weight    19,795 Da
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 NCBI Official Full Name    neurotensin/neuromedin N preproprotein
 NCBI Official Synonym Full Names    neurotensin
 NCBI Official Symbol    NTS [Similar Products]
 NCBI Official Synonym Symbols   
NN; NT; NT/N; NTS1; NMN-125
[Similar Products]
 NCBI Protein Information    neurotensin/neuromedin N
 UniProt Protein Name    Neurotensin/neuromedin N
 UniProt Synonym Protein Names   
Large neuromedin NAlternative name(s):NmN-125
 Protein Family    Neurotensin
 UniProt Gene Name    NTS [Similar Products]
 UniProt Synonym Gene Names    NN; NmN; NT [Similar Products]
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 NCBI Summary for NT    This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]
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 UniProt Comments for NT    NTS: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. Belongs to the neurotensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q21.31

Cellular Component: extracellular region; nerve terminal

Molecular Function: neuropeptide hormone activity
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 Research Articles on NT    1. findings directly link NT with increased fat absorption and obesity and suggest that NT may provide a prognostic marker of future obesity and a potential target for prevention and treatment
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NT small moleculePathways associated with NT small molecule
 Reference Product  PubMed Publications
 CCK small molecule  >107 publications with NT and CCK
 NTSR1 small molecule  >10 publications with NT and NTSR1
 NTSR2 small molecule  >7 publications with NT and NTSR2
 GRP small molecule  >4 publications with NT and GRP
 TAC1 small molecule  >3 publications with NT and TAC1
 NMU small molecule  >1 publications with NT and NMU
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with NT small moleculeOrgans/Tissues associated with NT small molecule
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >387 publications with NT and Cardiovascular Diseases
 Hypertension Antibodies  >346 publications with NT and Hypertension
 Nervous System Diseases Antibodies  >280 publications with NT and Nervous System Diseases
 Bradycardia Antibodies  >258 publications with NT and Bradycardia
 Hypotension Antibodies  >184 publications with NT and Hypotension
 Inflammation Antibodies  >163 publications with NT and Inflammation
 Brain Diseases Antibodies  >149 publications with NT and Brain Diseases
 Disease Models, Animal Antibodies  >144 publications with NT and Disease Models, Animal
 Kidney Diseases Antibodies  >106 publications with NT and Kidney Diseases
 Pain Antibodies  >95 publications with NT and Pain
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2956 publications with NT and Brain
 Heart Antibodies  >789 publications with NT and Heart
 Kidney Antibodies  >188 publications with NT and Kidney
 Stomach Antibodies  >139 publications with NT and Stomach
 Intestine Antibodies  >69 publications with NT and Intestine
 Skin Antibodies  >47 publications with NT and Skin
 Mouth Antibodies  >46 publications with NT and Mouth
 Connective Tissue Antibodies  >27 publications with NT and Connective Tissue
 Pancreas Antibodies  >23 publications with NT and Pancreas
 Ovary Antibodies  >18 publications with NT and Ovary
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