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G-CSF western blot control :: Granulocyte Colony Stimulating Factor (G-CSF) Western Blot Control

Scan QR to view Datasheet Catalog #    MBS343037 G-CSF western blot control
Unit / Price
0.01 mg  /  $205 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Granulocyte Colony Stimulating Factor (G-CSF), Western Blot Control

 Also Known As   

Granulocyte Colony Stimulating Factor (G-CSF) (Western Blot Control)

 Product Synonym Names    Granulocyte Colony Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF; Granulocyte Colony Stimulating Factor (Western Blot Control)
 Product Gene Name   

G-CSF western blot control

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138970
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 Purity/Purification    >= 95% (SDS PAGE)
 Form/Format    Liquid
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 Buffer    Buffered 50% glycerol
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 ISO Certification    Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
 Other Notes    Small volumes of G-CSF western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for G-CSF western blot control

   G-CSF is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. G-CSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of neutrophil granulocyte progenator cells and mature neutrophils. Recombinant G-CSF comprises a 174 amino acid fragment (31-204) corresponding to the mature short form of the G-CSF protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
 Product Categories/Family for G-CSF western blot control    Recombinant Proteins; G-CSF
NCBI/Uniprot data below describe general gene information for G-CSF. It may not necessarily be applicable to this product.
 NCBI GI #    194303452
 NCBI GeneID    1440
 NCBI Accession #    ACF41164.1 [Other Products]
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 UniProt Secondary Accession #    A8MXR7 [Other Products]
 UniProt Related Accession #    P09919 [Other Products]
 Molecular Weight    18,434 Da
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 NCBI Official Full Name    granulocyte colony stimulating factor, partial
 NCBI Official Synonym Full Names    colony stimulating factor 3
 NCBI Official Symbol    CSF3 [Similar Products]
 NCBI Official Synonym Symbols   
GCSF; CSF3OS; C17orf33
[Similar Products]
 NCBI Protein Information    granulocyte colony-stimulating factor
 UniProt Protein Name    Granulocyte colony-stimulating factor
 UniProt Synonym Protein Names   
Pluripoietin; INN: Filgrastim; INN: Lenograstim
 UniProt Gene Name    CSF3 [Similar Products]
 UniProt Synonym Gene Names    C17orf33; GCSF; G-CSF [Similar Products]
 UniProt Entry Name    CSF3_HUMAN
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 NCBI Summary for G-CSF    The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
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 UniProt Comments for G-CSF    G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular region

Molecular Function: cytokine activity; enzyme binding; growth factor activity

Biological Process: multicellular organismal development; positive regulation of actin filament polymerization; positive regulation of myeloid cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein binding; positive regulation of protein kinase B signaling cascade; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter
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Product References and Citations for G-CSF western blot control

   Nagata, S. (1989), Bioessays 10(4): 113-117.
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 Research Articles on G-CSF    1. G-CSF stimulates beta1 integrin expression and Swan 71 cell migration by activating PI3K and MAPK signaling pathways.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with G-CSF western blot controlDiseases associated with G-CSF western blot control
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with G-CSF and Nervous System Diseases
 Neutropenia Antibodies  >5 publications with G-CSF and Neutropenia
 Leukopenia Antibodies  >3 publications with G-CSF and Leukopenia
 Breast Neoplasms Antibodies  >3 publications with G-CSF and Breast Neoplasms
 Leukemia, Myeloid, Acute Antibodies  >3 publications with G-CSF and Leukemia, Myeloid, Acute
 Neoplasm Metastasis Antibodies  >3 publications with G-CSF and Neoplasm Metastasis
 Gastrointestinal Diseases Antibodies  >2 publications with G-CSF and Gastrointestinal Diseases
 Brain Injuries Antibodies  >2 publications with G-CSF and Brain Injuries
 Anemia Antibodies  >2 publications with G-CSF and Anemia
 Hypertrophy Antibodies  >2 publications with G-CSF and Hypertrophy
Organs/Tissues associated with G-CSF western blot control
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >11 publications with G-CSF and Lung
 Muscle Antibodies  >9 publications with G-CSF and Muscle
 Skin Antibodies  >9 publications with G-CSF and Skin
 Brain Antibodies  >6 publications with G-CSF and Brain
 Uterus Antibodies  >5 publications with G-CSF and Uterus
 Intestine Antibodies  >3 publications with G-CSF and Intestine
 Liver Antibodies  >2 publications with G-CSF and Liver
 Uncharacterized Tissue Antibodies  >1 publications with G-CSF and Uncharacterized Tissue
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