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MAOB western blot control :: Monoamine Oxidase B (MAOB) Western Blot Control

Scan QR to view Datasheet Catalog #    MBS343092 MAOB western blot control
Unit / Price
0.01 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Monoamine Oxidase B (MAOB), Western Blot Control

 Also Known As   

Monoamine Oxidase B (MAOB) (Western Blot Control)

 Product Synonym Names    Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAOB, Mao Platelet, MAO Brain; MAOB (Western Blot Control)
 Product Gene Name   

MAOB western blot control

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    309860
 3D Structure    ModBase 3D Structure for P27338
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 Purity/Purification    >= 95% (SDS PAGE)
 Form/Format    Liquid
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 Buffer    Buffered 50% glycerol
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 ISO Certification    Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
 Other Notes    Small volumes of MAOB western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MAOB western blot control

   Monoamine oxidase B (MAO-B) is a flavin-containing mitochondrial enzyme, which catalyzes the oxidative deamination of biogenic and xenobiotic monoamines. It regulates the metabolic degradation of catecholamines and serotonin in neural and other target tissues. MAO-B is found platelets and in dopamine-secreting neurons in the brain. Increased levels of MAO B that have been identified in brain of Alzheimer's patients. Monoamine oxidases (MAO B and MAO A) are well-known targets for antidepressant drugs and for drugs used to treat neurological disorders and aging diseases, such as Parkinson's and Alzheimer's disease. Recombinant MAO-B comprises a 488 amino acid fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature MAO-B protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
 Product Categories/Family for MAOB western blot control    Recombinant Proteins; Monoamine Oxidase B
NCBI/Uniprot data below describe general gene information for MAOB. It may not necessarily be applicable to this product.
 NCBI GI #    398415
 NCBI GeneID    4129
 NCBI Accession #    AAB27229.1 [Other Products]
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 UniProt Primary Accession #    P27338 [Other Products]
 UniProt Secondary Accession #    Q7Z6S2; B2R6R3; B7Z5H3; D3DWC3 [Other Products]
 UniProt Related Accession #    P27338 [Other Products]
 Molecular Weight    46,539 Da
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 NCBI Official Full Name    monoamine oxidase B, partial
 NCBI Official Synonym Full Names    monoamine oxidase B
 NCBI Official Symbol    MAOB [Similar Products]
 NCBI Protein Information    amine oxidase [flavin-containing] B
 UniProt Protein Name    Amine oxidase [flavin-containing] B
 UniProt Synonym Protein Names   
Monoamine oxidase type B; MAO-B
 Protein Family    Amine oxidase
 UniProt Gene Name    MAOB [Similar Products]
 UniProt Synonym Gene Names    MAO-B [Similar Products]
 UniProt Entry Name    AOFB_HUMAN
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 NCBI Summary for MAOB    The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MAOB    MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family.

Protein type: Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - histidine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.4.3.4; Oxidoreductase; Membrane protein, integral; Amino Acid Metabolism - phenylalanine; Mitochondrial; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - glycine, serine and threonine

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion

Molecular Function: amine oxidase activity; electron carrier activity

Biological Process: dopamine catabolic process; substantia nigra development
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Product References and Citations for MAOB western blot control

   Binda, C. et al., Neurology 2006 67: S5-S7. Li, M. et al., Protei Expr Purif. 2002 24 (1): 152-62.
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 Research Articles on MAOB    1. Report isolation of MOA-B inhibitors from Vernonia cinerea.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MAOB western blot controlDiseases associated with MAOB western blot control
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Amine Oxidase Reactions Pathway antibodies  Amine Oxidase Reactions Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Biogenic Amines Are Oxidatively Deaminated To Aldehydes By MAOA And MAOB Pathway antibodies  Biogenic Amines Are Oxidatively Deaminated To Aldehydes By MAOA And MAOB Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Disease Name  Pubmed Publications
 Movement Disorders Antibodies  >50 publications with MAOB and Movement Disorders
 Parkinson Disease Antibodies  >45 publications with MAOB and Parkinson Disease
 Schizophrenia Antibodies  >17 publications with MAOB and Schizophrenia
 Neurobehavioral Manifestations Antibodies  >16 publications with MAOB and Neurobehavioral Manifestations
 Alzheimer Disease Antibodies  >6 publications with MAOB and Alzheimer Disease
 Autistic Disorder Antibodies  >6 publications with MAOB and Autistic Disorder
 Depressive Disorder Antibodies  >6 publications with MAOB and Depressive Disorder
 Inflammation Antibodies  >4 publications with MAOB and Inflammation
 Learning Disorders Antibodies  >4 publications with MAOB and Learning Disorders
 Neurotoxicity Syndromes Antibodies  >3 publications with MAOB and Neurotoxicity Syndromes
Organs/Tissues associated with MAOB western blot control
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >74 publications with MAOB and Brain
 Nerve Antibodies  >15 publications with MAOB and Nerve
 Liver Antibodies  >9 publications with MAOB and Liver
 Eye Antibodies  >7 publications with MAOB and Eye
 Muscle Antibodies  >6 publications with MAOB and Muscle
 Adrenal Gland Antibodies  >5 publications with MAOB and Adrenal Gland
 Kidney Antibodies  >5 publications with MAOB and Kidney
 Skin Antibodies  >3 publications with MAOB and Skin
 Connective Tissue Antibodies  >3 publications with MAOB and Connective Tissue
 Adipose Tissue Antibodies  >3 publications with MAOB and Adipose Tissue
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