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PRL western blot control :: Prolactin Western Blot Control

Scan QR to view Datasheet Catalog #    MBS343117 PRL western blot control
Unit / Price
0.01 mg  /  $205 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Prolactin (PRL), Western Blot Control

 Also Known As   

Prolactin (Western Blot Control)

 Product Synonym Names    PRL, Mammotropin, Luteotropic hormone, Luteotropin
 Product Gene Name   

PRL western blot control

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176760
 3D Structure    ModBase 3D Structure for P01236
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 Purity/Purification    >= 95% (SDS PAGE)
 Form/Format    Liquid
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 Buffer    Buffered 50% glycerol
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 ISO Certification    Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
 Other Notes    Small volumes of PRL western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for PRL western blot control

   Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation. Recombinant prolactin comprises a 199 amino acid fragment (29-227) corresponding to the mature prolactin protein and is expressed in E Coliwith an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
 Product Categories/Family for PRL western blot control    Recombinant Proteins; Prolactin
NCBI/Uniprot data below describe general gene information for PRL. It may not necessarily be applicable to this product.
 NCBI GI #    531103
 NCBI GeneID    5617
 NCBI Accession #    CAA38264.1 [Other Products]
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 UniProt Primary Accession #    P01236 [Other Products]
 UniProt Secondary Accession #    Q15199; Q92996 [Other Products]
 UniProt Related Accession #    P01236 [Other Products]
 Molecular Weight    25,876 Da [Similar Products]
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 NCBI Official Full Name    prolactin
 NCBI Official Synonym Full Names    prolactin
 NCBI Official Symbol    PRL [Similar Products]
 NCBI Official Synonym Symbols   
GHA1
[Similar Products]
 NCBI Protein Information    prolactin
 UniProt Protein Name    Prolactin
 Protein Family    Prolactin
 UniProt Gene Name    PRL [Similar Products]
 UniProt Synonym Gene Names    PRL [Similar Products]
 UniProt Entry Name    PRL_HUMAN
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 NCBI Summary for PRL    This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
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 UniProt Comments for PRL    prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Cytokine; Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: extracellular region

Molecular Function: prolactin receptor binding; protein binding

Biological Process: cell proliferation; cell surface receptor linked signal transduction; cellular protein metabolic process; positive regulation of JAK-STAT cascade; regulation of multicellular organism growth
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Product References and Citations for PRL western blot control

   Harris, J. et al (2004) Ann. Med. 36(6): 414-425. Kelly, P.A. et al (1991) Endocr. Rev 12(3):235-251.
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 Research Articles on PRL    1. findings revealed that the -1149TT genotype was correlated with higher levels of prolactin in serum and prolactin gene expression in peripheral blood mononuclear cells in women with systemic lupus erythematosus; study suggests that the -1149TT genotype may be a risk factor for lupus
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRL western blot controlPathways associated with PRL western blot control
 Reference Product  PubMed Publications
 TRH western blot control  >1765 publications with PRL and TRH
 PRLR western blot control  >393 publications with PRL and PRLR
 JAK2 western blot control  >202 publications with PRL and JAK2
 POU1F1 western blot control  >147 publications with PRL and POU1F1
 STAT5A western blot control  >86 publications with PRL and STAT5A
 STAT3 western blot control  >75 publications with PRL and STAT3
 GHR western blot control  >58 publications with PRL and GHR
 STAT5B western blot control  >48 publications with PRL and STAT5B
 ESR1 western blot control  >15 publications with PRL and ESR1
 BMP1 western blot control  >2 publications with PRL and BMP1
 Products by Pathway  Pathway Diagram
 Amyloid Fiber Formation Pathway antibodies  Amyloid Fiber Formation Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 ErbB4 Signaling Events Pathway antibodies  ErbB4 Signaling Events Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Growth Hormone Receptor Signaling Pathway antibodies  Growth Hormone Receptor Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with PRL western blot controlOrgans/Tissues associated with PRL western blot control
 Disease Name  Pubmed Publications
 Pituitary Neoplasms Antibodies  >2068 publications with PRL and Pituitary Neoplasms
 Hyperprolactinemia Antibodies  >1568 publications with PRL and Hyperprolactinemia
 Adenoma Antibodies  >1545 publications with PRL and Adenoma
 Prolactinoma Antibodies  >720 publications with PRL and Prolactinoma
 Mental Disorders Antibodies  >625 publications with PRL and Mental Disorders
 Amenorrhea Antibodies  >432 publications with PRL and Amenorrhea
 Galactorrhea Antibodies  >324 publications with PRL and Galactorrhea
 Growth Hormone-Secreting Pituitary Adenoma Antibodies  >272 publications with PRL and Growth Hormone-Secreting Pituitary Adenoma
 Infertility, Female Antibodies  >253 publications with PRL and Infertility, Female
 Hypogonadism Antibodies  >219 publications with PRL and Hypogonadism
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5215 publications with PRL and Brain
 Pituitary Gland Antibodies  >4036 publications with PRL and Pituitary Gland
 Uterus Antibodies  >539 publications with PRL and Uterus
 Testis Antibodies  >506 publications with PRL and Testis
 Placenta Antibodies  >407 publications with PRL and Placenta
 Heart Antibodies  >213 publications with PRL and Heart
 Eye Antibodies  >206 publications with PRL and Eye
 Muscle Antibodies  >201 publications with PRL and Muscle
 Connective Tissue Antibodies  >123 publications with PRL and Connective Tissue
 Uncharacterized Tissue Antibodies  >1 publications with PRL and Uncharacterized Tissue
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