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TNFb western blot control :: Tumor Necrosis Factor Beta (TNFb) Western Blot Control

Scan QR to view Datasheet Catalog #    MBS343143 TNFb western blot control
Unit / Price
0.01 mg  /  $180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor Necrosis Factor Beta (TNFb), Western Blot Control

 Also Known As   

Tumor Necrosis Factor Beta (TNFb) (Western Blot Control)

 Product Synonym Names    TNF?, Lymphotoxin alpha, LT?, TNFSF1, TNF superfamily � member 1.
 Product Gene Name   

TNFb western blot control

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P26445
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 Purity/Purification    >= 95% (SDS PAGE)
 Form/Format    Liquid
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 Buffer    Buffered 50% glycerol
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 ISO Certification    Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
 Other Notes    Small volumes of TNFb western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for TNFb western blot control

   TNF beta is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on Tumor cells and a variety of other target cells as well as being a mediator of inflammation and immune function. Recombinant TNF beta comprises a 171 amino acid fragment (35-205) corresponding to the mature TNF beta chain protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
 Product Categories/Family for TNFb western blot control    Recombinant Proteins; Tumor Necrosis Factor Beta
NCBI/Uniprot data below describe general gene information for TNFb. It may not necessarily be applicable to this product.
 NCBI GI #    2133
 NCBI GeneID    407742
 NCBI Accession #    CAA38638.1 [Other Products]
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 UniProt Primary Accession #    P26445 [Other Products]
 UniProt Secondary Accession #    A5D9N9 [Other Products]
 UniProt Related Accession #    P26445 [Other Products]
 Molecular Weight    21,960 Da
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 NCBI Official Full Name    Tumour necrosis factor beta
 NCBI Official Symbol    LTA [Similar Products]
 NCBI Official Synonym Symbols   
TNFB
[Similar Products]
 NCBI Protein Information    lymphotoxin-alpha
 UniProt Protein Name    Lymphotoxin-alpha
 UniProt Synonym Protein Names   
TNF-beta; Tumor necrosis factor ligand superfamily member 1
 UniProt Gene Name    LTA [Similar Products]
 UniProt Synonym Gene Names    TNFB; TNFSF1; LT-alpha [Similar Products]
 UniProt Entry Name    TNFB_PIG
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 UniProt Comments for TNFb    Function: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.

Subunit structure: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits

Subcellular location: Secreted

By similarity. Membrane

By similarity. Note: The homotrimer is secreted

By similarity. The heterotrimer is membrane-associated

Sequence similarities: Belongs to the tumor necrosis factor family.
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Product References and Citations for TNFb western blot control

   Ruddle, N.H. (1992) Curr. Opin. Immunol. 4(3): 327-332. Porter, A.G. (1990) FEMS Microbiol. Immunol. 2(4): 193-199.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFb western blot controlPathways associated with TNFb western blot control
 Reference Product  PubMed Publications
 LTB western blot control  >114 publications with TNFb and LTB
 IFNG western blot control  >12 publications with TNFb and IFNG
 CD40 western blot control  >8 publications with TNFb and CD40
 TNFRSF1A western blot control  >8 publications with TNFb and TNFRSF1A
 LTBR western blot control  >7 publications with TNFb and LTBR
 TNFRSF1B western blot control  >7 publications with TNFb and TNFRSF1B
 RELB western blot control  >3 publications with TNFb and RELB
 RIPK1 western blot control  >3 publications with TNFb and RIPK1
 TANK western blot control  >2 publications with TNFb and TANK
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
Diseases associated with TNFb western blot controlOrgans/Tissues associated with TNFb western blot control
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >413 publications with TNFb and Necrosis
 Inflammation Antibodies  >396 publications with TNFb and Inflammation
 Cardiovascular Diseases Antibodies  >254 publications with TNFb and Cardiovascular Diseases
 Heart Diseases Antibodies  >162 publications with TNFb and Heart Diseases
 Lung Diseases Antibodies  >116 publications with TNFb and Lung Diseases
 Sepsis Antibodies  >114 publications with TNFb and Sepsis
 Myocardial Infarction Antibodies  >90 publications with TNFb and Myocardial Infarction
 Coronary Artery Disease Antibodies  >86 publications with TNFb and Coronary Artery Disease
 Disease Models, Animal Antibodies  >76 publications with TNFb and Disease Models, Animal
 Liver Diseases Antibodies  >53 publications with TNFb and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >879 publications with TNFb and Blood
 Adrenal Gland Antibodies  >6 publications with TNFb and Adrenal Gland
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