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Product Name
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Tumor Type M2 Pyruvate Kinase (M2PK), Western Blot Control
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Also Known As
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Tumor Type M2 Pyruvate Kinase (M2PK) (Western Blot Control)
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Product Synonym Names
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M2PK, PKM2, Pyruvate kinase 3 isoform 2
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Product Gene Name
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[Similar Products]
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Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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Purity/Purification
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>= 95% (SDS PAGE)
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Form/Format
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Liquid
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Buffer
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Buffered 50% glycerol
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ISO Certification
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Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
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Other Notes
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Small volumes of M2PK western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in Tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence. Recombinant human M2PK is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
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Product Categories/Family for M2PK western blot control
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Recombinant Proteins; M2PK
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Luftner D. et al. (2000) Anticancer Res. 20(6D): 5077-82.
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Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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