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A4GALT cdna clone

Scan QR to view Datasheet Catalog #    MBS1278132 A4GALT cdna clone
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A4GALT, cDNA Clone

 Also Known As   

A4GALT cDNA Clone

 Product Gene Name   

A4GALT cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    111400
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of A4GALT cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for A4GALT. It may not necessarily be applicable to this product.
 NCBI GI #    34190882
 NCBI GeneID    53947
 NCBI Accession #    BC017068 [Other Products]
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 UniProt Secondary Accession #    Q9P1X5; B2R7C4 [Other Products]
 UniProt Related Accession #    Q9NPC4 [Other Products]
 Molecular Weight    40,499 Da
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 NCBI Official Full Name    Homo sapiens alpha 1,4-galactosyltransferase, mRNA
 NCBI Official Synonym Full Names    alpha 1,4-galactosyltransferase
 NCBI Official Symbol    A4GALT [Similar Products]
 NCBI Official Synonym Symbols   
P1; PK; Gb3S; P(k); P1PK; A14GALT; A4GALT1
[Similar Products]
 NCBI Protein Information    lactosylceramide 4-alpha-galactosyltransferase
 UniProt Protein Name    Lactosylceramide 4-alpha-galactosyltransferase
 UniProt Synonym Protein Names   
Alpha-1,4-N-acetylglucosaminyltransferase; Alpha-1,4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
 Protein Family    Lactosylceramide 4-alpha-galactosyltransferase
 UniProt Gene Name    A4GALT [Similar Products]
 UniProt Synonym Gene Names    A14GALT; A4GALT1; Gb3 synthase [Similar Products]
 UniProt Entry Name    A4GAT_HUMAN
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 NCBI Summary for A4GALT    The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
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 UniProt Comments for A4GALT    A4GALT: Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. Belongs to the glycosyltransferase 32 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Transferase; Membrane protein, integral; EC 2.4.1.228

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: membrane

Molecular Function: galactosyltransferase activity

Biological Process: plasma membrane organization and biogenesis

Disease: Blood Group, P1pk System
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 Research Articles on A4GALT    1. This is the first direct biochemical evidence that Gb3/CD77 synthase is able to synthesize two different glycosphingolipid antigens: P(k) and P1, and when p.Q211E substitution is present, the NOR antigen is also synthesized.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with A4GALT cdna cloneDiseases associated with A4GALT cdna clone
 Products by Pathway  Pathway Diagram
 Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies  Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies  Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
 Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway antibodies  Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway Diagram
 Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway antibodies  Glycosphingolipid Biosynthesis, Globo-series, LacCer => Gb4Cer Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >2 publications with A4GALT and Immune System Diseases
 Drug Toxicity Antibodies  >1 publications with A4GALT and Drug Toxicity
 Inflammation Antibodies  >1 publications with A4GALT and Inflammation
 Lymphoma Antibodies  >1 publications with A4GALT and Lymphoma
 Carcinoma Antibodies  >1 publications with A4GALT and Carcinoma
 Immunologic Deficiency Syndromes Antibodies  >1 publications with A4GALT and Immunologic Deficiency Syndromes
Organs/Tissues associated with A4GALT cdna clone
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with A4GALT and Bone
 Ovary Antibodies  >1 publications with A4GALT and Ovary
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