BC015096
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
96,217 Da
NCBI Official Full Name
Homo sapiens aminoadipate-semialdehyde dehydrogenase, mRNA
NCBI Official Synonym Full Names
aminoadipate-semialdehyde dehydrogenase
NCBI Protein Information
acyl-CoA synthetase family member 4
UniProt Protein Name
Acyl-CoA synthetase family member 4
UniProt Synonym Protein Names
Aminoadipate-semialdehyde dehydrogenase; Protein NRPS998
UniProt Synonym Gene Names
UniProt Entry Name
ACSF4_HUMAN
NCBI Summary for AASDH
This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues. [provided by RefSeq, Apr 2016]
UniProt Comments for AASDH
AASDH: Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Belongs to the ATP-dependent AMP-binding enzyme family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - lysine biosynthesis; EC 1.2.1.31; Amino Acid Metabolism - lysine degradation; Ligase; Oxidoreductase
Chromosomal Location of Human Ortholog: 4q12
Molecular Function: acid-thiol ligase activity
Biological Process: fatty acid metabolic process
Research Articles on AASDH
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Organs/Tissues associated with AASDH cdna clone
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