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ABCA3 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274144 ABCA3 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCA3, cDNA Clone

 Also Known As   

ABCA3 cDNA Clone

 Product Gene Name   

ABCA3 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctgtgc tcaggcagct ggcgctcctc ctctggaaga actacaccct gcagaagcgg aaggtcctgg tgacggtcct ggaactcttc ctgccattgc tgttttctgg gatcctcatc tggctccgct tgaagattca gtcggaaaat gtgcccaacg ccaccatcta cccgggccag tccatccagg agctgcctct gttcttcacc ttccctccgc caggagacac ctgggagctt gcctacatcc cttctcacag tgacgctgcc aagaccgtca ctgagacagt gcgcagggca cttgtgatca acatgcgagt gcgcggcttt ccctccgaga aggactttga ggactacatt aggtacgaca actgctcgtc cagcgtgctg gccgccgtgg tcttcgagca ccccttcaac cacagcaagg agcccctgcc gctggcggtg aaatatcacc tacggttcag ttacacacgg agaaattaca tgtggaccca aacaggctcc tttttcctga aagagacaga aggctggcac actacttccc ttttcccgct tttcccaaac ccaggaccaa gggaacctac atcccctgat ggcggagaac ctggtgagaa gctcggttag
 OMIM    601615
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCA3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCA3. It may not necessarily be applicable to this product.
 NCBI GI #    38541007
 NCBI GeneID    21
 NCBI Accession #    BC062779 [Other Products]
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 UniProt Secondary Accession #    Q54A95; Q6P5P9; Q92473; B2RU09 [Other Products]
 UniProt Related Accession #    Q99758 [Other Products]
 Molecular Weight    24,002 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily A member 3
 NCBI Official Symbol    ABCA3 [Similar Products]
 NCBI Official Synonym Symbols   
ABC3; ABC-C; SMDP3; LBM180; EST111653
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family A member 3
 UniProt Protein Name    ATP-binding cassette sub-family A member 3
 UniProt Synonym Protein Names   
ABC-C transporter; ATP-binding cassette transporter 3; ATP-binding cassette 3
 Protein Family    ABC transporter A family
 UniProt Gene Name    ABCA3 [Similar Products]
 UniProt Synonym Gene Names    ABC3; ATP-binding cassette 3 [Similar Products]
 UniProt Entry Name    ABCA3_HUMAN
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 NCBI Summary for ABCA3    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCA3    ABCA3: Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3); also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Belongs to the ABC transporter superfamily. ABCA family.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ABC family

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space; membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; lipid transporter activity; transporter activity

Biological Process: cellular protein metabolic process; lipid transport; response to drug; transmembrane transport; transport

Disease: Surfactant Metabolism Dysfunction, Pulmonary, 3
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 Research Articles on ABCA3    1. Data discussed the structural features of ABCA3 and how the use of bioinformatics tools could help researchers to obtain a reliable structural model to locate relevant mutations and make genotype/phenotype correlations of affected patients. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCA3 cdna cloneDiseases associated with ABCA3 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >78 publications with ABCA3 and Lung Diseases
 Neoplasms Antibodies  >21 publications with ABCA3 and Neoplasms
 Fibrosis Antibodies  >11 publications with ABCA3 and Fibrosis
 Brain Diseases Antibodies  >8 publications with ABCA3 and Brain Diseases
 Inflammation Antibodies  >7 publications with ABCA3 and Inflammation
 Death Antibodies  >7 publications with ABCA3 and Death
 Hyperplasia Antibodies  >6 publications with ABCA3 and Hyperplasia
 Lung Neoplasms Antibodies  >6 publications with ABCA3 and Lung Neoplasms
 Adenocarcinoma Antibodies  >5 publications with ABCA3 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >4 publications with ABCA3 and Cardiovascular Diseases
Organs/Tissues associated with ABCA3 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >109 publications with ABCA3 and Lung
 Brain Antibodies  >14 publications with ABCA3 and Brain
 Thyroid Antibodies  >13 publications with ABCA3 and Thyroid
 Vascular Antibodies  >7 publications with ABCA3 and Vascular
 Kidney Antibodies  >6 publications with ABCA3 and Kidney
 Skin Antibodies  >5 publications with ABCA3 and Skin
 Heart Antibodies  >5 publications with ABCA3 and Heart
 Pancreas Antibodies  >3 publications with ABCA3 and Pancreas
 Testis Antibodies  >3 publications with ABCA3 and Testis
 Trachea Antibodies  >2 publications with ABCA3 and Trachea
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