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ABCB5 cdna clone

Scan QR to view Datasheet Catalog #    MBS1269141 ABCB5 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCB5, cDNA Clone

★Popular Item★
 Also Known As   

ABCB5 cDNA Clone

 Product Gene Name   

ABCB5 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    ATGGTGGATG AGAATGACAT CAGAGCTTTA AATGTGCGGC ATTATCGAGA CCATATTGGA GTGGTTAGTC AAGAGCCTGT TTTGTTCGGG ACCACCATCA GTAACAATAT CAAGTATGGA CGAGATGATG TGACTGATGA AGAGATGGAG AGAGCAGCAA GGGAAGCAAA TGCGTATGAT TTTATCATGG AGTTTCCTAA TAAATTTAAT ACATTGGTAG GGGAAAAAGG AGCTCAAATG AGTGGAGGGC AGAAACAGAG GATCGCAATT GCTCGTGCCT TAGTTCGAAA CCCCAAGATT CTGATTTTAG ATGAGGCTAC GTCTGCCCTG GATTCAGAAA GCAAGTCAGC TGTTCAAGCT GCACTGGAGA AGGCGAGCAA AGGTCGGACT ACAATCGTGG TAGCACACCG ACTTTCTACT ATTCGAAGTG CAGATTTGAT TGTGACCCTA AAGGATGGAA TGCTGGCGGA GAAAGGAGCA CATGCTGAAC TAATGGCAAA ACGAGGTCTA TATTATTCAC TTGTGATGTC ACAGGATATT AAAAAAGCTG ATGAACAGAT GGAGTCAATG ACATATTCTA CTGAAAGAAA GACCAACTCA CTTCCTCTGC ACTCTGTGAA GAGCATCAAG TCAGACTTCA TTGACAAGGC TGAGGAATCC ACCCAATCTA AAGAGATAAG TCTTCCTGAA GTCTCTCTAT TAAAAATTTT AAAGTTAAAC AAGCCTGAAT GGCCTTTTGT GGTTCTGGGG ACATTGGCTT CTGTTCTAAA TGGAACTGTT CATCCAGTAT TTTCCATCAT CTTTGCAAAA ATTATAACCA TGTTTGGAAA TAATGATAAA ACCACATTAA AGCATGATGC AGAAATTTAT TCCATGATAT TCGTCATTTT GGGTGTTATT TGCTTTGTCA GTTATTTCAT GCAGGGATTA TTTTACGGCA GAGCAGGGGA AATTTTAACG ATGAGATTAA GACACTTGGC CTTCAAAGCC ATGTTATATC AGGATATTGC CTGGTTTGAT GAAAAGGAAA ACAGCACAGG AGGCTTGACA ACAATATTAG CCATAGATAT AGCACAAATT CAAGGAGCAA CAGGTTCCAG GATTGGCGTC TTAACACAAA ATGCAACTAA CATGGGACTT TCAGTTATCA TTTCCTTTAT ATATGGATGG GAGATGACAT TCCTGATTCT GAGTATTGCT CCAGTACTTG CCGTGACAGG AATGATTGAA ACCGCAGCAA TGACTGGATT TGCCAACAAA GATAAGCAAG AACTTAAGCA TGCTGGAAAG ATAGCAACTG AAGCTTTGGA GAATATACGT ACTATAGTGT CATTAACAAG GGAAAAAGCC TTCGAGCAAA TGTATGAAGA GATGCTTCAG ACTCAACACA GAAATACCTC GAAGAAAGCA CAGATTATTG GAAGCTGTTA TGCATTCAGC CATGCCTTTA TATATTTTGC CTATGCGGCA GGGTTTCGAT TTGGAGCCTA TTTAATTCAA GCTGGACGAA TGACCCCAGA GGGCATGTTC ATAGTTTTTA CTGCAATTGC ATATGGAGCT ATGGCCATCG GAGAAACGCT CGTTTTGGCT CCTGAATATT CCAAAGCCAA ATCGGGGGCT GCGCATCTGT TTGCCTTGTT GGAAAAGAAA CCAAATATAG ACAGCCGCAG TCAAGAAGGG AAAAAGCCAG ACACATGTGA AGGGAATTTA GAGTTTCGAG AAGTCTCTTT CTTCTATCCA TGTCGCCCAG ATGTTTTCAT CCTCCGTGGC TTATCCCTCA GTATTGAGCG AGGAAAGACA GTAGCATTTG TGGGGAGCAG CGGCTGTGGG AAAAGCACTT CTGTTCAACT TCTGCAGAGA CTTTATGACC CCGTGCAAGG ACAAGTGCTG TTTGATGGTG TGGATGCAAA AGAATTGAAT GTACAGTGGC TCCGTTCCCA AATAGCAATC GTTCCTCAAG AGCCTGTGCT CTTCAACTGC AGCATTGCTG AGAACATCGC CTATGGTGAC AACAGCCGTG TGGTGCCATT AGATGAGATC AAAGAAGCCG CAAATGCAGC AAATATCCAT TCTTTTATTG AAGGTCTCCC TGAGAAATAC AACACACAAG TTGGACTGAA AGGAGCACAG CTTTCTGGCG GCCAGAAACA AAGACTAGCT ATTGCAAGGG CTCTTCTCCA AAAACCCAAA ATTTTATTGT TGGATGAGGC CACTTCAGCC CTCGATAATG ACAGTGAGAA GGTGGTTCAG CATGCCCTTG ATAAAGCCAG GACGGGAAGG ACATGCCTAG TGGTCACTCA CAGGCTCTCT GCAATTCAGA ACGCAGATTT GATAGTGGTT CTGCACAATG GAAAGATAAA GGAACAAGGA ACTCATCAAG AGCTCCTGAG AAATCGAGAC ATATATTTTA AGTTAGTGAA TGCACAGTCA GTGCAGTGA
 OMIM    611785
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCB5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCB5. It may not necessarily be applicable to this product.
 NCBI GI #    85397771
 NCBI GeneID    340273
 NCBI Accession #    BC104894 [Other Products]
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 UniProt Secondary Accession #    Q2M3I5; Q5I5Q7; Q5I5Q8; Q6KG50; A4D131; A7BKA4; B5MD19; B7WPL1; F8QQP8; F8QQP9; J3KQ04 [Other Products]
 UniProt Related Accession #    Q2M3G0 [Other Products]
 Molecular Weight    89,832 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 5, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily B member 5
 NCBI Official Symbol    ABCB5 [Similar Products]
 NCBI Official Synonym Symbols   
ABCB5beta; EST422562; ABCB5alpha
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family B member 5
 UniProt Protein Name    ATP-binding cassette sub-family B member 5
 UniProt Synonym Protein Names   
ABCB5 P-gp; P-glycoprotein ABCB5
 Protein Family    ABC transporter B family
 UniProt Gene Name    ABCB5 [Similar Products]
 UniProt Entry Name    ABCB5_HUMAN
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 NCBI Summary for ABCB5    ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for ABCB5    ABCB5: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas. Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ABC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; efflux transmembrane transporter activity; xenobiotic-transporting ATPase activity

Biological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; compound eye corneal lens development; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; regulation of membrane potential; transmembrane transport
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 Research Articles on ABCB5    1. ABCB5 has a role in chemoresistance in Merkel Cell Carcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCB5 cdna cloneDiseases associated with ABCB5 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Melanoma Antibodies  >44 publications with ABCB5 and Melanoma
 Leukemia, Myeloid, Acute Antibodies  >3 publications with ABCB5 and Leukemia, Myeloid, Acute
 Lung Neoplasms Antibodies  >2 publications with ABCB5 and Lung Neoplasms
 Disease Models, Animal Antibodies  >2 publications with ABCB5 and Disease Models, Animal
 Head and Neck Neoplasms Antibodies  >1 publications with ABCB5 and Head and Neck Neoplasms
 Skin Abnormalities Antibodies  >1 publications with ABCB5 and Skin Abnormalities
Organs/Tissues associated with ABCB5 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >22 publications with ABCB5 and Skin
 Testis Antibodies  >3 publications with ABCB5 and Testis
 Intestine Antibodies  >2 publications with ABCB5 and Intestine
 Kidney Antibodies  >1 publications with ABCB5 and Kidney
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