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ABCB8 cdna clone

Scan QR to view Datasheet Catalog #    MBS1269031 ABCB8 cdna clone
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCB8, cDNA Clone

 Also Known As   

ABCB8 cDNA Clone

 Product Gene Name   

ABCB8 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    605464
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCB8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCB8. It may not necessarily be applicable to this product.
 NCBI GI #    146327013
 NCBI GeneID    11194
 NCBI Accession #    BC141814 [Other Products]
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 UniProt Secondary Accession #    O95787; Q53GM0; A5D8W3; B2RBL8; B3KND2; B4DG02; G3XAP3 [Other Products]
 UniProt Related Accession #    Q9NUT2 [Other Products]
 Molecular Weight    59,383 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily B member 8
 NCBI Official Symbol    ABCB8 [Similar Products]
 NCBI Official Synonym Symbols   
MABC1; M-ABC1; EST328128
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family B member 8, mitochondrial
 UniProt Protein Name    ATP-binding cassette sub-family B member 8, mitochondrial
 UniProt Synonym Protein Names   
Mitochondrial ATP-binding cassette 1; M-ABC1
 Protein Family    ATP-binding cassette sub-family
 UniProt Gene Name    ABCB8 [Similar Products]
 UniProt Synonym Gene Names    MABC1; M-ABC1 [Similar Products]
 UniProt Entry Name    ABCB8_HUMAN
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 NCBI Summary for ABCB8    This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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 UniProt Comments for ABCB8    ABCB8: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Hydrolase; Transporter, ABC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: ATP-binding cassette (ABC) transporter complex; membrane; mitochondrial envelope; mitochondrion; nucleolus; nucleus

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; transporter activity

Biological Process: transmembrane transport; transport
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 Research Articles on ABCB8    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCB8 cdna cloneDiseases associated with ABCB8 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 Mitochondrial ABC Transporters Pathway antibodies  Mitochondrial ABC Transporters Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with ABCB8 and Neoplasms
 Skin Neoplasms Antibodies  >2 publications with ABCB8 and Skin Neoplasms
 Heart Defects, Congenital Antibodies  >1 publications with ABCB8 and Heart Defects, Congenital
 Congenital Abnormalities Antibodies  >1 publications with ABCB8 and Congenital Abnormalities
 Anemia Antibodies  >1 publications with ABCB8 and Anemia
 Death Antibodies  >1 publications with ABCB8 and Death
 Inflammation Antibodies  >1 publications with ABCB8 and Inflammation
 Heart Diseases Antibodies  >1 publications with ABCB8 and Heart Diseases
Organs/Tissues associated with ABCB8 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with ABCB8 and Blood
 Heart Antibodies  >2 publications with ABCB8 and Heart
 Skin Antibodies  >2 publications with ABCB8 and Skin
 Muscle Antibodies  >1 publications with ABCB8 and Muscle
 Liver Antibodies  >1 publications with ABCB8 and Liver
 Spleen Antibodies  >1 publications with ABCB8 and Spleen
 Lung Antibodies  >1 publications with ABCB8 and Lung
 Testis Antibodies  >1 publications with ABCB8 and Testis
 Brain Antibodies  >1 publications with ABCB8 and Brain
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