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ABCB9 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274160 ABCB9 cdna clone
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCB9, cDNA Clone

 Also Known As   

ABCB9 cDNA Clone

 Product Gene Name   

ABCB9 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    605453
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCB9 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCB9. It may not necessarily be applicable to this product.
 NCBI GI #    40226059
 NCBI GeneID    23457
 NCBI Accession #    BC017348 [Other Products]
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 UniProt Secondary Accession #    Q5W9G7; Q769F3; Q769F4; Q96AB1; Q9P208; B4E2J0 [Other Products]
 UniProt Related Accession #    Q9NP78 [Other Products]
 Molecular Weight    77,470 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 9, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily B member 9
 NCBI Official Symbol    ABCB9 [Similar Products]
 NCBI Official Synonym Symbols   
TAPL; EST122234
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family B member 9
 UniProt Protein Name    ATP-binding cassette sub-family B member 9
 UniProt Synonym Protein Names   
ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL
 Protein Family    ABC transporter B family
 UniProt Gene Name    ABCB9 [Similar Products]
 UniProt Synonym Gene Names    KIAA1520; ABC transporter 9 protein; hABCB9; TAPL [Similar Products]
 UniProt Entry Name    ABCB9_HUMAN
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 NCBI Summary for ABCB9    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]
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 UniProt Comments for ABCB9    ABCB9: ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ABC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: early endosome; endoplasmic reticulum; integral to endoplasmic reticulum membrane; integral to membrane; lysosomal membrane; lysosome

Molecular Function: ATP binding; oligopeptide-transporting ATPase activity; peptide-transporting ATPase activity; protein binding; protein homodimerization activity; substrate-specific transmembrane transporter activity

Biological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; peptide transport; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; transmembrane transport
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 Research Articles on ABCB9    1. The structure of the unique domain of TAPL, is reported.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCB9 cdna cloneOrgans/Tissues associated with ABCB9 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >5 publications with ABCB9 and Intestine
 Brain Antibodies  >3 publications with ABCB9 and Brain
 Testis Antibodies  >2 publications with ABCB9 and Testis
 Bone Antibodies  >1 publications with ABCB9 and Bone
 Lung Antibodies  >1 publications with ABCB9 and Lung
 Thymus Antibodies  >1 publications with ABCB9 and Thymus
 Liver Antibodies  >1 publications with ABCB9 and Liver
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