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ABCC4 cdna clone

Scan QR to view Datasheet Catalog #    MBS1270623 ABCC4 cdna clone
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCC4, cDNA Clone

 Also Known As   

ABCC4 cDNA Clone

 Product Gene Name   

ABCC4 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    605250
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCC4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCC4. It may not necessarily be applicable to this product.
 NCBI GI #    27371327
 NCBI GeneID    10257
 NCBI Accession #    BC041560 [Other Products]
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 UniProt Secondary Accession #    Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2; A9Z1Z7; B7Z3Q7 [Other Products]
 UniProt Related Accession #    O15439 [Other Products]
 Molecular Weight    88,138 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily C member 4
 NCBI Official Symbol    ABCC4 [Similar Products]
 NCBI Official Synonym Symbols   
MRP4; MOATB; MOAT-B
[Similar Products]
 NCBI Protein Information    multidrug resistance-associated protein 4
 UniProt Protein Name    Multidrug resistance-associated protein 4
 UniProt Synonym Protein Names   
ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B
 Protein Family    ABC transporter C family
 UniProt Gene Name    ABCC4 [Similar Products]
 UniProt Synonym Gene Names    MRP4; MOAT-B [Similar Products]
 UniProt Entry Name    MRP4_HUMAN
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 NCBI Summary for ABCC4    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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 UniProt Comments for ABCC4    ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family

Chromosomal Location of Human Ortholog: 13q32

Cellular Component: basolateral plasma membrane; membrane; plasma membrane; platelet dense granule membrane

Molecular Function: anion transmembrane-transporting ATPase activity; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

Biological Process: cilium biogenesis; platelet degranulation; prostaglandin secretion; transmembrane transport
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 Research Articles on ABCC4    1. MRP4 overexpression is important to reduce aspirin-selective cell death
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCC4 cdna cloneDiseases associated with ABCC4 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Drug Induction Of Bile Acid Pathway antibodies  Drug Induction Of Bile Acid Pathway Diagram
 Fluoropyrimidine Activity Pathway antibodies  Fluoropyrimidine Activity Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >68 publications with ABCC4 and Neoplasms
 Drug Toxicity Antibodies  >37 publications with ABCC4 and Drug Toxicity
 Cholestasis Antibodies  >17 publications with ABCC4 and Cholestasis
 Liver Diseases Antibodies  >15 publications with ABCC4 and Liver Diseases
 Inflammation Antibodies  >11 publications with ABCC4 and Inflammation
 Adenocarcinoma Antibodies  >10 publications with ABCC4 and Adenocarcinoma
 Necrosis Antibodies  >7 publications with ABCC4 and Necrosis
 Brain Diseases Antibodies  >7 publications with ABCC4 and Brain Diseases
 Kidney Diseases Antibodies  >7 publications with ABCC4 and Kidney Diseases
 Liver Neoplasms Antibodies  >7 publications with ABCC4 and Liver Neoplasms
Organs/Tissues associated with ABCC4 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >100 publications with ABCC4 and Blood
 Liver Antibodies  >66 publications with ABCC4 and Liver
 Kidney Antibodies  >61 publications with ABCC4 and Kidney
 Brain Antibodies  >40 publications with ABCC4 and Brain
 Vascular Antibodies  >17 publications with ABCC4 and Vascular
 Intestine Antibodies  >16 publications with ABCC4 and Intestine
 Lung Antibodies  >14 publications with ABCC4 and Lung
 Muscle Antibodies  >11 publications with ABCC4 and Muscle
 Prostate Antibodies  >8 publications with ABCC4 and Prostate
 Bone Antibodies  >7 publications with ABCC4 and Bone
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