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ABCD3 cdna clone

Scan QR to view Datasheet Catalog #    MBS1272423 ABCD3 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCD3, cDNA Clone

 Also Known As   

ABCD3 cDNA Clone

 Product Gene Name   

ABCD3 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcggcct tcagcaagta cttgacggcg cgaaactcct cgctggctgg tgccgcgttc ctgctgctct gcctgctcca caagcggcgc cgcgccctcg gcctgcacgg taagaaaagt ggaaaaccac cattacagaa caatgagaaa gaggggaaaa aggagcgagc tgtggtggac aaggtgtttt tctcaaggct catacagatt ctgaaaatca tggtccctag aacattttgt aaagagacag gttacttggt acttattgct gttatgctgg tgtctcgaac atattgtgat gtttggatga ttcaaaatgg gacactaatt gaaagtggta tcattggtcg tagcaggaaa gatttcaaga gatacttact caacttcatc gctgccatgc ctcttatctc tctggttaat aacttcttga agtatgggtt aaatgagctt aaactgtgct tccgagtaag gctcactaaa tacctctatg aggagtatct tcaagctttc acatattata aaatggggaa tctggacaac agaatagcta atccagacca gctgcttaca caagatgtag aaaaattttg taacagtgta gtcgatctgt attcaaatct tagtaagcca tttttagaca tagttttgta tatctttaag ttaacgagtg caattggagc tcaggtactt ggaaaaattt tgtggcatta a
 OMIM    170995
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCD3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCD3. It may not necessarily be applicable to this product.
 NCBI GI #    34783258
 NCBI GeneID    5825
 NCBI Accession #    BC009712 [Other Products]
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 UniProt Secondary Accession #    Q15271; Q6NUN5; Q96DA3; Q9H529; D3DT46 [Other Products]
 UniProt Related Accession #    P28288 [Other Products]
 Molecular Weight    27,121 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family D (ALD), member 3, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily D member 3
 NCBI Official Symbol    ABCD3 [Similar Products]
 NCBI Official Synonym Symbols   
ZWS2; ABC43; CBAS5; PMP70; PXMP1
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family D member 3
 UniProt Protein Name    ATP-binding cassette sub-family D member 3
 UniProt Synonym Protein Names   
70 kDa peroxisomal membrane protein; PMP70
 Protein Family    ABC transporter D family
 UniProt Gene Name    ABCD3 [Similar Products]
 UniProt Synonym Gene Names    PMP70; PXMP1; PMP70 [Similar Products]
 UniProt Entry Name    ABCD3_HUMAN
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 NCBI Summary for ABCD3    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCD3    ABCD3: a member of the superfamily of ATP-binding cassette (ABC) transporters. Likely plays an important role in peroxisome biogenesis. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. Defects in ABCD3 may be the cause of Zellweger syndrome-2 (ZWS-2), an autosomal recessive disorder due to defective import mechanisms for peroxisomal matrix enzymes.

Protein type: Membrane protein, multi-pass; Mitochondrial; Membrane protein, integral; Transporter; Transporter, ABC family

Chromosomal Location of Human Ortholog: 1p21.3

Cellular Component: cytosol; intracellular membrane-bound organelle; membrane; peroxisomal matrix; peroxisomal membrane; peroxisome

Molecular Function: ATP binding; ATPase activity; long-chain fatty acid transporter activity; protein binding; protein homodimerization activity

Biological Process: fatty acid beta-oxidation; fatty acid biosynthetic process; peroxisome organization and biogenesis; transmembrane transport; very-long-chain fatty acid catabolic process

Disease: Bile Acid Synthesis Defect, Congenital, 5
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 Research Articles on ABCD3    1. Increased ABCD3 expression correlates with Gleason Score.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCD3 cdna cloneDiseases associated with ABCD3 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 Nuclear Receptors In Lipid Metabolism And Toxicity Pathway antibodies  Nuclear Receptors In Lipid Metabolism And Toxicity Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Zellweger Syndrome Antibodies  >15 publications with ABCD3 and Zellweger Syndrome
 Liver Diseases Antibodies  >14 publications with ABCD3 and Liver Diseases
 Kidney Diseases Antibodies  >11 publications with ABCD3 and Kidney Diseases
 Neoplasms Antibodies  >8 publications with ABCD3 and Neoplasms
 Necrosis Antibodies  >3 publications with ABCD3 and Necrosis
 Weight Gain Antibodies  >1 publications with ABCD3 and Weight Gain
 Skin Neoplasms Antibodies  >1 publications with ABCD3 and Skin Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with ABCD3 and Carcinoma, Hepatocellular
Organs/Tissues associated with ABCD3 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >33 publications with ABCD3 and Liver
 Vascular Antibodies  >5 publications with ABCD3 and Vascular
 Skin Antibodies  >4 publications with ABCD3 and Skin
 Intestine Antibodies  >3 publications with ABCD3 and Intestine
 Embryonic Tissue Antibodies  >2 publications with ABCD3 and Embryonic Tissue
 Placenta Antibodies  >1 publications with ABCD3 and Placenta
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