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ABCG4 cdna clone

Scan QR to view Datasheet Catalog #    MBS1270457 ABCG4 cdna clone
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCG4, cDNA Clone

 Also Known As   

ABCG4 cDNA Clone

 Product Gene Name   

ABCG4 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    607784
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABCG4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCG4. It may not necessarily be applicable to this product.
 NCBI GI #    26996514
 NCBI GeneID    64137
 NCBI Accession #    BC041091 [Other Products]
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 UniProt Secondary Accession #    Q8WWH0; Q8WWH1; Q8WWH2; A8K1B5 [Other Products]
 UniProt Related Accession #    Q9H172 [Other Products]
 Molecular Weight    60,903 Da
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 NCBI Official Full Name    Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 4, mRNA
 NCBI Official Synonym Full Names    ATP binding cassette subfamily G member 4
 NCBI Official Symbol    ABCG4 [Similar Products]
 NCBI Official Synonym Symbols   
WHITE2
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family G member 4
 UniProt Protein Name    ATP-binding cassette sub-family G member 4
 Protein Family    ABC transporter G family
 UniProt Gene Name    ABCG4 [Similar Products]
 UniProt Synonym Gene Names    WHITE2 [Similar Products]
 UniProt Entry Name    ABCG4_HUMAN
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 NCBI Summary for ABCG4    The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCG4    ABCG4: May be involved in macrophage lipid homeostasis. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.

Protein type: Transporter, ABC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: cholesterol transporter activity; protein binding; protein heterodimerization activity; protein homodimerization activity; sterol-transporting ATPase activity

Biological Process: cholesterol efflux; transmembrane transport
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 Research Articles on ABCG4    1. Study suggests that high ABCG4 expression is associated with poor prognosis in patients with non-small-cell lung cancer with advanced stages.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCG4 cdna cloneDiseases associated with ABCG4 cdna clone
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >5 publications with ABCG4 and Liver Diseases
 Nervous System Diseases Antibodies  >4 publications with ABCG4 and Nervous System Diseases
 Drug Toxicity Antibodies  >1 publications with ABCG4 and Drug Toxicity
 Congenital Abnormalities Antibodies  >1 publications with ABCG4 and Congenital Abnormalities
Organs/Tissues associated with ABCG4 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >19 publications with ABCG4 and Brain
 Eye Antibodies  >4 publications with ABCG4 and Eye
 Testis Antibodies  >3 publications with ABCG4 and Testis
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