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ABI2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274929 ABI2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABI2, cDNA Clone

 Also Known As   

ABI2 cDNA Clone

 Product Gene Name   

ABI2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcggagc tgcagatgct gctggaagag gaaatcccgg ggggccgccg ggccctcttc gacagctaca caaatctgga acgggtggcc gattactgcg agaacaacta catacagtca gcagataagc agagagccct agaagaaacc aaagcctaca ccacccaatc cttagcaagt gttgcctatc tgataaacac cttggccaac aatgtcctgc agatgctgga tatccaggca tcccagctac gaaggatgga atcttcaatc aatcatattt cacaaacagt tgatattcat aaagagaaag ttgcaagaag agaaattggt attttgacta ccaataaaaa cacttcaagg acacataaga ttattgctcc agccaacctt gaacgaccag ttcgttatat tagaaaacct attgactata caattctaga tgatattgga catggagtaa aggtgagtac ccagaacatg aagatgggtg ggctgccgcg tacaacacct ccaactcaga agccccctag tccccctatg tcagggaaag ggacacttgg gcggcactcc ccctatcgca cactggagcc agtgcgtcct ccagtggtac caaatgatta cgtacctagc ccaacccgta atatggctcc ctcgcagcag agccctgtga ggacagcttc tgtgaatcaa agaaatcgaa cttacagcag cagtgggagt agtggaggga gccacccaag tagtcggagc agcagtcgag agaacagtgg aagtggtagt gtgggggttc ctattgctgt tcctactcca tctcctccca gtgtctttcc aggtcatcct gtacagttct acagcatgaa taggcctgcc tctcgccata ctcccccaac aatagggggc tcgttgccct atagacgccc tccttccatt acttcacaaa caagccttca gaatcagatg aatggaggac ctttttatag ccagaatcca gtatctcttg ctcctcctcc tccctccatc ctacaggtaa ctcctcagtt acctttaatg ggatttgtgg ccagagtcca agaaaatatt tcagatacac cacctccacc gccacctgtg gaagaaccag tctttgatga gtctccccca cctcctcctc ctccagaaga ttacgaagag gaggaagctg ctgtggttga gtatagtgat ccttatgctg aagaggaccc accgtgggct ccacgttctt acttggaaaa ggttgtggca atttatgact atacaaaaga caaggaagat gagctgtcct ttcaggaagg agccattatt tatgtcatca agaagaatga cgatggttgg tatgagggag ttatgaatgg agtgactggg ctttttcctg ggaattacgt tgagtctatc atgcattatt ctgagtaa
 OMIM    606442
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABI2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABI2. It may not necessarily be applicable to this product.
 NCBI GI #    37589013
 NCBI GeneID    10152
 NCBI Accession #    BC001439 [Other Products]
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 UniProt Secondary Accession #    Q13147; Q13249; Q13801; Q9BV70; B4DSN1 [Other Products]
 UniProt Related Accession #    Q9NYB9 [Other Products]
 Molecular Weight    54,819 Da
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 NCBI Official Full Name    Homo sapiens abl interactor 2, mRNA
 NCBI Official Synonym Full Names    abl interactor 2
 NCBI Official Symbol    ABI2 [Similar Products]
 NCBI Official Synonym Symbols   
ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB
[Similar Products]
 NCBI Protein Information    abl interactor 2
 UniProt Protein Name    Abl interactor 2
 UniProt Synonym Protein Names   
Abelson interactor 2; Abi-2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1
 Protein Family    Abl interactor
 UniProt Gene Name    ABI2 [Similar Products]
 UniProt Synonym Gene Names    ARGBPIA; Abi-2; AblBP3; ArgBP1 [Similar Products]
 UniProt Entry Name    ABI2_HUMAN
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 UniProt Comments for ABI2    Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: cytoplasm; cytosol; filopodium; lamellipodium

Molecular Function: cytoskeletal adaptor activity; DNA binding; protein binding; protein complex binding; Rac GTPase binding; SH3 domain binding; ubiquitin protein ligase binding

Biological Process: cell migration; cell motility; cytoskeleton organization and biogenesis; peptidyl-tyrosine phosphorylation; Rac protein signal transduction
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 Research Articles on ABI2    1. Abl-interactor 2 (ABI2) is a novel MLL translocation partner in acute myeloid leukemia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABI2 cdna cloneDiseases associated with ABI2 cdna clone
 Products by Pathway  Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 RAC1 Signaling Pathway antibodies  RAC1 Signaling Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies  Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >10 publications with ABI2 and Neoplasms
 Nervous System Diseases Antibodies  >4 publications with ABI2 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with ABI2 and Cell Transformation, Neoplastic
 Neurobehavioral Manifestations Antibodies  >2 publications with ABI2 and Neurobehavioral Manifestations
 Necrosis Antibodies  >2 publications with ABI2 and Necrosis
 Neoplasms, Experimental Antibodies  >1 publications with ABI2 and Neoplasms, Experimental
 Drug Toxicity Antibodies  >1 publications with ABI2 and Drug Toxicity
 Carcinoma Antibodies  >1 publications with ABI2 and Carcinoma
 Weight Loss Antibodies  >1 publications with ABI2 and Weight Loss
 Neoplasm Metastasis Antibodies  >1 publications with ABI2 and Neoplasm Metastasis
Organs/Tissues associated with ABI2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with ABI2 and Brain
 Thyroid Antibodies  >9 publications with ABI2 and Thyroid
 Vascular Antibodies  >9 publications with ABI2 and Vascular
 Blood Antibodies  >6 publications with ABI2 and Blood
 Heart Antibodies  >4 publications with ABI2 and Heart
 Muscle Antibodies  >3 publications with ABI2 and Muscle
 Embryonic Tissue Antibodies  >3 publications with ABI2 and Embryonic Tissue
 Eye Antibodies  >2 publications with ABI2 and Eye
 Nerve Antibodies  >2 publications with ABI2 and Nerve
 Bone Antibodies  >2 publications with ABI2 and Bone
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