View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List ABI2 cdna clone Catalog # MBS1274929 Unit / Price 0.01 mg Plasmid + 0.2 mL Glycerol-Stock / $205 +1 FREE 8GB USB 5x0.01 mg Plasmid + 5x0.2 mL Glycerol-Stock / $915 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name ABI2, cDNA Clone Full Product Name ABI2 cDNA Clone Product Gene Name ABI2 cdna clone[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence atggcggagc tgcagatgct gctggaagag gaaatcccgg ggggccgccg ggccctcttc gacagctaca caaatctgga acgggtggcc gattactgcg agaacaacta catacagtca gcagataagc agagagccct agaagaaacc aaagcctaca ccacccaatc cttagcaagt gttgcctatc tgataaacac cttggccaac aatgtcctgc agatgctgga tatccaggca tcccagctac gaaggatgga atcttcaatc aatcatattt cacaaacagt tgatattcat aaagagaaag ttgcaagaag agaaattggt attttgacta ccaataaaaa cacttcaagg acacataaga ttattgctcc agccaacctt gaacgaccag ttcgttatat tagaaaacct attgactata caattctaga tgatattgga catggagtaa aggtgagtac ccagaacatg aagatgggtg ggctgccgcg tacaacacct ccaactcaga agccccctag tccccctatg tcagggaaag ggacacttgg gcggcactcc ccctatcgca cactggagcc agtgcgtcct ccagtggtac caaatgatta cgtacctagc ccaacccgta atatggctcc ctcgcagcag agccctgtga ggacagcttc tgtgaatcaa agaaatcgaa cttacagcag cagtgggagt agtggaggga gccacccaag tagtcggagc agcagtcgag agaacagtgg aagtggtagt gtgggggttc ctattgctgt tcctactcca tctcctccca gtgtctttcc aggtcatcct gtacagttct acagcatgaa taggcctgcc tctcgccata ctcccccaac aatagggggc tcgttgccct atagacgccc tccttccatt acttcacaaa caagccttca gaatcagatg aatggaggac ctttttatag ccagaatcca gtatctcttg ctcctcctcc tccctccatc ctacaggtaa ctcctcagtt acctttaatg ggatttgtgg ccagagtcca agaaaatatt tcagatacac cacctccacc gccacctgtg gaagaaccag tctttgatga gtctccccca cctcctcctc ctccagaaga ttacgaagag gaggaagctg ctgtggttga gtatagtgat ccttatgctg aagaggaccc accgtgggct ccacgttctt acttggaaaa ggttgtggca atttatgact atacaaaaga caaggaagat gagctgtcct ttcaggaagg agccattatt tatgtcatca agaagaatga cgatggttgg tatgagggag ttatgaatgg agtgactggg ctttttcctg ggaattacgt tgagtctatc atgcattatt ctgagtaa OMIM 606442 Vector pENTR223.1 or pUC Clone Sequence Report Provided with product shipment ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of ABI2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for ABI2. It may not necessarily be applicable to this product. NCBI GI # 37589013 NCBI GeneID 10152 NCBI Accession # BC001439 [Other Products] UniProt Secondary Accession # Q13147; Q13249; Q13801; Q9BV70; B4DSN1[Other Products] UniProt Related Accession # Q9NYB9[Other Products] Molecular Weight 54,819 Da TOP NCBI Official Full Name Homo sapiens abl interactor 2, mRNA NCBI Official Synonym Full Names abl interactor 2 NCBI Official Symbol ABI2 [Similar Products] NCBI Official Synonym Symbols ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB [Similar Products] NCBI Protein Information abl interactor 2 UniProt Protein Name Abl interactor 2 UniProt Synonym Protein Names Abelson interactor 2; Abi-2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1 Protein Family Abl interactor UniProt Gene Name ABI2 [Similar Products] UniProt Synonym Gene Names ARGBPIA; Abi-2; AblBP3; ArgBP1 [Similar Products] UniProt Entry Name ABI2_HUMAN TOP TOP UniProt Comments for ABI2 Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffold; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 2q33Cellular Component: cytoplasm; cytosol; filopodium; lamellipodiumMolecular Function: cytoskeletal adaptor activity; DNA binding; protein binding; protein complex binding; Rac GTPase binding; SH3 domain binding; ubiquitin protein ligase bindingBiological Process: cell migration; cell motility; cytoskeleton organization and biogenesis; peptidyl-tyrosine phosphorylation; Rac protein signal transduction Research Articles on ABI2 1. Abl-interactor 2 (ABI2) is a novel MLL translocation partner in acute myeloid leukemia. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. 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TOP Pathways associated with ABI2 cdna clone Products by Pathway Pathway Diagram Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Innate Immune System Pathway antibodies Innate Immune System Pathway Diagram RAC1 Signaling Pathway antibodies RAC1 Signaling Pathway Diagram Regulation Of Actin Cytoskeleton Pathway antibodies Regulation Of Actin Cytoskeleton Pathway Diagram Regulation Of Actin Cytoskeleton Pathway antibodies Regulation Of Actin Cytoskeleton Pathway Diagram Regulation Of Actin Cytoskeleton Pathway antibodies Regulation Of Actin Cytoskeleton Pathway Diagram Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram Diseases associated with ABI2 cdna clone Disease Name Pubmed Publications Neoplasms Antibodies >10 publications with ABI2 and Neoplasms Nervous System Diseases Antibodies >4 publications with ABI2 and Nervous System Diseases Cell Transformation, Neoplastic Antibodies >3 publications with ABI2 and Cell Transformation, Neoplastic Neurobehavioral Manifestations Antibodies >2 publications with ABI2 and Neurobehavioral Manifestations Necrosis Antibodies >2 publications with ABI2 and Necrosis Neoplasms, Experimental Antibodies >1 publications with ABI2 and Neoplasms, Experimental Drug Toxicity Antibodies >1 publications with ABI2 and Drug Toxicity Carcinoma Antibodies >1 publications with ABI2 and Carcinoma Weight Loss Antibodies >1 publications with ABI2 and Weight Loss Neoplasm Metastasis Antibodies >1 publications with ABI2 and Neoplasm Metastasis Organs/Tissues associated with ABI2 cdna clone Organ/Tissue Name Pubmed Publications Brain Antibodies >15 publications with ABI2 and Brain Thyroid Antibodies >9 publications with ABI2 and Thyroid Vascular Antibodies >9 publications with ABI2 and Vascular Blood Antibodies >6 publications with ABI2 and Blood Heart Antibodies >4 publications with ABI2 and Heart Muscle Antibodies >3 publications with ABI2 and Muscle Embryonic Tissue Antibodies >3 publications with ABI2 and Embryonic Tissue Eye Antibodies >2 publications with ABI2 and Eye Nerve Antibodies >2 publications with ABI2 and Nerve Bone Antibodies >2 publications with ABI2 and Bone TOP © 2006-24 MyBioSource.com. 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