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ABI3 cdna clone

Scan QR to view Datasheet Catalog #    MBS1270266 ABI3 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABI3, cDNA Clone

 Also Known As   

ABI3 cDNA Clone

 Product Gene Name   

ABI3 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcggagc tacagcagct gcaggagttt gagatcccca ctggccggga ggctctgagg ggcaaccaca gtgccctgct gcgggtcgct gactactgcg aggacaacta tgtgcaggcc acagacaagc ggaaggcgct ggaggagacc atggccttca ctacccaggc actggccagc gtggcctacc aggtgggcaa cctggccggg cacactctgc gcatgttgga cctgcagggg gccgccctgc ggcaggtgga agcccgtgta agcacgctgg gccagatggt gaacatgcat atggagaagg tggcccgaag ggagatcggc accttagcca ctgtccagcg gctgcccccc ggccagaagg tcatcgcccc agagaaccta ccccctctca cgccctactg caggagaccc ctcaactttg gctgcctgga cgacattggc catgggatca aggacctcag cacgcagctg tcaagaacag gcaccctgtc tcgaaagagc atcaaggccc ctgccacacc cgcctccgcc accttgggga gaccaccccg gattcccgag ccagtgcacc tgccggtggt gcccgacggc agactctccg ccgcctcctc tgcgtcttcc ctggcctcgg ccggcagcgc cgaaggtgtc ggtggggccc ccacgcccaa ggggcaggca gcacctccag ccccacctct ccccagctcc ttggacccac ctcctccacc agcagccgtc gaggtgttcc agcggcctcc cacgctggag gagttgtccc cacccccacc ggacgaagag ctgcccctgc cactggacct gcctcctcct ccacccctgg atggagatga attggggctg cctccacccc caccaggatt tgggcctgat gagcccagct gggtgcctgc ctcatacttg gagaaagtgg tgacactgta cccatacacc agccagaagg acaatgagct ctccttctct gagggcactg tcatctgtgt cactcgccgc tactccgatg gctggtgcga gggcgtcagc tcagagggga ctggattctt ccctgggaac tatgtggagc ccagctgctg a
 OMIM    606363
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABI3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABI3. It may not necessarily be applicable to this product.
 NCBI GI #    39644798
 NCBI GeneID    51225
 NCBI Accession #    BC007780 [Other Products]
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 UniProt Secondary Accession #    Q9H0P6; C9IZN8 [Other Products]
 UniProt Related Accession #    Q9P2A4 [Other Products]
 Molecular Weight    38,450 Da
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 NCBI Official Full Name    Homo sapiens ABI family, member 3, mRNA
 NCBI Official Synonym Full Names    ABI family member 3
 NCBI Official Symbol    ABI3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    ABI gene family member 3
 UniProt Protein Name    ABI gene family member 3
 UniProt Synonym Protein Names   
New molecule including SH3; Nesh
 Protein Family    ABI gene family
 UniProt Gene Name    ABI3 [Similar Products]
 UniProt Synonym Gene Names    NESH; Nesh [Similar Products]
 UniProt Entry Name    ABI3_HUMAN
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 NCBI Summary for ABI3    This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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 UniProt Comments for ABI3    ABI3: May inhibit tumor metastasis. In vitro, reduces cell motility. Belongs to the ABI family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: cytoplasm; intracellular; lamellipodium; membrane

Molecular Function: protein binding

Biological Process: peptidyl-tyrosine phosphorylation; regulation of cell migration
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 Research Articles on ABI3    1. Result links ABI3 to the pathogenesis and progression of some cancers and suggests that ABI3 or its pathway might have interest as therapeutic target.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ABI3 cdna clone
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with ABI3 and Carcinoma
 Neoplasms, Experimental Antibodies  >1 publications with ABI3 and Neoplasms, Experimental
 Neoplasm Metastasis Antibodies  >1 publications with ABI3 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >1 publications with ABI3 and Adenocarcinoma
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