BC007422
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,230 Da
NCBI Official Full Name
Homo sapiens acid phosphatase 1, soluble, mRNA
NCBI Official Synonym Full Names
acid phosphatase 1, soluble
NCBI Protein Information
low molecular weight phosphotyrosine protein phosphatase
UniProt Protein Name
Low molecular weight phosphotyrosine protein phosphatase
UniProt Synonym Protein Names
Adipocyte acid phosphatase; Low molecular weight cytosolic acid phosphatase (EC:3.1.3.2); Red cell acid phosphatase 1
UniProt Synonym Gene Names
UniProt Entry Name
PPAC_HUMAN
NCBI Summary for ACP1
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]
UniProt Comments for ACP1
ACP1: a phosphotyrosine protein phosphatase. Functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. Hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. Genetically polymorphic with three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene.
Protein type: Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.2; EC 3.1.3.48; Motility/polarity/chemotaxis; Phosphatase (non-protein); Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; internal side of plasma membrane
Molecular Function: protein binding
Research Articles on ACP1
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Pathways associated with ACP1 cdna clone
Diseases associated with ACP1 cdna clone
Organs/Tissues associated with ACP1 cdna clone
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