BC025378
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
81,603 Da
NCBI Official Full Name
Homo sapiens ADAM metallopeptidase domain 20, mRNA
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 20
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 20
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 20
UniProt Synonym Gene Names
UniProt Entry Name
ADA20_HUMAN
NCBI Summary for ADAM20
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene is testis-specific. [provided by RefSeq, Jul 2008]
UniProt Comments for ADAM20
ADAM20: May be involved in sperm maturation and/or fertilization.
Protein type: Protease; Membrane protein, integral; EC 3.4.24.-; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 14q24.1
Cellular Component: plasma membrane
Molecular Function: metallopeptidase activity
Biological Process: binding of sperm to zona pellucida; single fertilization
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Diseases associated with ADAM20 cdna clone
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