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ADAM22 cdna clone

Scan QR to view Datasheet Catalog #    MBS1272011 ADAM22 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAM22, cDNA Clone

★Popular Item★
 Also Known As   

ADAM22 cDNA Clone

 Product Gene Name   

ADAM22 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgcaggcgg cagtggctgt gtccgtgccc ttcttgctgc tctgtgtcct ggggacctgc cctccggcgc gctgcggcca ggcaggagac gcctcattga tggagctaga gaagaggaag gaaaaccgct tcgtggagcg ccagagcatc gtgccactgc gcctcatcta ccgctcgggc ggcgaagacg aaagtcggca cgacgcgctc gacacgcggg tgcggggcga cgtcggtggc ccgcagttga ctcatgttga ccaagcaagc ttccaggttg atgcctttgg aacgtcattc attctcgatg tcgtgctaaa tcatgatttg ctgtcctctg aatacataga gagacacatt gaacatggag gcaagactgt ggaagttaaa ggaggagagc actgttacta ccagggccat atccgaggaa accctgactc atttgttgca ttgtcaacat gccacggact tcatgggatg ttctatgacg ggaaccacac atatctcatt gagccagaag aaaatgacac tactcaagag gatttccatt ttcattcagt ttacaaatcc agactgtttg aattttcctt ggatgatctt ccatctgaat ttcagcaagt aaacattact ccatcaaaat ttattttgaa gccaagacca aaaaggagta aacggcagct tcgtcgatat cctcgtaatg tagaagaaga aaccaaatac attgaactga tgattgtgaa tgatcacctt atgtttaaaa aacatcggct ttccgttgta cataccaata cctatgcgaa atctgtggtg aacatggcag atttaatata taaagaccaa cttaagacca ggatagtatt ggttgctatg gaaacctggg cgactgacaa caagtttgcc atatctgaaa atccattgat caccctacgt gagtttatga aatacaggag ggattttatc aaagagaaaa gtgatgcagt tcaccttttt tcgtacgtaa cttctgtaat gatgtattac tttttttga
 Chromosome Location    Chromosome: 7; NC_000007.13 (87563566..87832204). Location: 7q21
 OMIM    603709
 3D Structure    ModBase 3D Structure for Q9P0K1
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ADAM22 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ADAM22. It may not necessarily be applicable to this product.
 NCBI GI #    23273565
 NCBI GeneID    53616
 NCBI Accession #    BC036029 [Other Products]
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 UniProt Primary Accession #    Q9P0K1 [Other Products]
 UniProt Secondary Accession #    O75075; O75076; Q9P0K2; Q9UIA1; Q9UKK2 [Other Products]
 UniProt Related Accession #    Q9P0K1 [Other Products]
 Molecular Weight    100,433 Da
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 NCBI Official Full Name    Homo sapiens ADAM metallopeptidase domain 22, mRNA
 NCBI Official Synonym Full Names    ADAM metallopeptidase domain 22
 NCBI Official Symbol    ADAM22 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    disintegrin and metalloproteinase domain-containing protein 22; metalloproteinase-disintegrin ADAM22-3; a disintegrin and metalloproteinase domain 22; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
 UniProt Protein Name    Disintegrin and metalloproteinase domain-containing protein 22
 UniProt Synonym Protein Names   
Metalloproteinase-disintegrin ADAM22-3; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAM22 [Similar Products]
 UniProt Synonym Gene Names    MDC2; ADAM 22 [Similar Products]
 UniProt Entry Name    ADA22_HUMAN
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 NCBI Summary for ADAM22    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]
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 UniProt Comments for ADAM22    ADAM22: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q21

Cellular Component: axon; integral to membrane

Molecular Function: integrin binding; protein binding; zinc ion binding; metalloendopeptidase activity

Biological Process: central nervous system development; adult locomotory behavior; negative regulation of cell adhesion; proteolysis; cell adhesion; myelination in the peripheral nervous system
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 Research Articles on ADAM22    1. findings suggest that SRC-1 switches steroid-responsive tumors to a steroid-resistant state in which the SRC-1 target gene ADAM22 has a critical role
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ADAM22 cdna cloneOrgans/Tissues associated with ADAM22 cdna clone
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >12 publications with ADAM22 and Nervous System Diseases
 Neoplasms Antibodies  >7 publications with ADAM22 and Neoplasms
 Memory Disorders Antibodies  >1 publications with ADAM22 and Memory Disorders
 Calcium Metabolism Disorders Antibodies  >1 publications with ADAM22 and Calcium Metabolism Disorders
 Inflammation Antibodies  >1 publications with ADAM22 and Inflammation
 Breast Neoplasms Antibodies  >1 publications with ADAM22 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >27 publications with ADAM22 and Nerve
 Brain Antibodies  >19 publications with ADAM22 and Brain
 Embryonic Tissue Antibodies  >6 publications with ADAM22 and Embryonic Tissue
 Eye Antibodies  >2 publications with ADAM22 and Eye
 Kidney Antibodies  >2 publications with ADAM22 and Kidney
 Skin Antibodies  >1 publications with ADAM22 and Skin
 Testis Antibodies  >1 publications with ADAM22 and Testis
 Ear Antibodies  >1 publications with ADAM22 and Ear
 Muscle Antibodies  >1 publications with ADAM22 and Muscle
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