BC026169
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
87,948 Da
NCBI Official Full Name
Homo sapiens ADAM metallopeptidase domain 32, mRNA
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 32
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 32
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 32
UniProt Synonym Gene Names
UniProt Entry Name
ADA32_HUMAN
NCBI Summary for ADAM32
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
UniProt Comments for ADAM32
ADAM32: May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.
Protein type: Protease; Motility/polarity/chemotaxis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 8p11.22
Research Articles on ADAM32
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Organs/Tissues associated with ADAM32 cdna clone
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